Yin Ning, Wang Ao-Xiang, Wang Hai-Li
State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, China.
Tianjin Key Laboratory of Bioelectromagnetic Technology and Intelligent Health, Hebei University of Technology, Tianjin, China.
Front Neurosci. 2022 Apr 5;16:848308. doi: 10.3389/fnins.2022.848308. eCollection 2022.
Magnetic stimulation has some similarities with acupuncture, and it has broad application prospects because of its non-invasiveness and easy quantification. This paper combines magnetic stimulation technology with electroencephalography to analyze the time-frequency and the brain functional network results elicited by magnetic stimulation at different acupoints. This paper hopes to observe the different effects of stimulating different acupoints on the brain from the perspective of EEG. The EEG signals during magnetic stimulation at ST36, ST40, and GB37 were recorded, respectively. The time-frequency results showed that the magnetic stimulation at ST36 and ST40 on the Foot Yangming Stomach Meridian increased the energy in the left parietal lobe and the right central region, and the energy increased mainly in the theta and alpha bands. However, during the magnetic stimulation at GB37 on the Foot Shaoyang Gallbladder Meridian, the energy in the central region and the frontal lobe increased, and the energy increased mainly in the delta, theta, and alpha bands. Moreover, the energy in the right parietal lobe decreased during magnetic stimulation at GB37. The results of brain functional network were also consistent with time-frequency results. The brain network connections of GB37 stimulation in the central region were significantly less than that of ST36 and ST40 ( < 0.01). In addition, the connections between central region and frontal lobe and the connections between central region and parietal lobe of GB37 stimulation were significantly different from that of ST36 and ST40 ( < 0.01). The above results indicate that ST36 and ST40 on the same meridian have similar effects on the brain, while GB37 on the other meridian has completely different effects from ST36 and ST40. The results of this paper explain the reason why stimulating ST36 and ST40 can treat similar diseases from the perspective of EEG, and also explain that stimulating GB37 has significantly different effects on the brain from that of ST36 and ST40.
磁刺激与针灸有一些相似之处,并且由于其非侵入性和易于量化而具有广阔的应用前景。本文将磁刺激技术与脑电图相结合,分析不同穴位磁刺激所引发的时频及脑功能网络结果。本文希望从脑电图的角度观察刺激不同穴位对大脑的不同影响。分别记录了在足三里(ST36)、丰隆(ST40)和阳陵泉(GB37)进行磁刺激时的脑电图信号。时频结果显示,足阳明胃经上的足三里(ST36)和丰隆(ST40)磁刺激增加了左顶叶和右中央区域的能量,且能量主要在θ和α频段增加。然而,在足少阳胆经上的阳陵泉(GB37)磁刺激期间,中央区域和额叶的能量增加,且能量主要在δ、θ和α频段增加。此外,在阳陵泉(GB37)磁刺激期间右顶叶的能量下降。脑功能网络结果也与时频结果一致。阳陵泉(GB37)刺激在中央区域的脑网络连接明显少于足三里(ST36)和丰隆(ST40)(<0.01)。此外,阳陵泉(GB37)刺激的中央区域与额叶之间的连接以及中央区域与顶叶之间的连接与足三里(ST36)和丰隆(ST40)明显不同(<0.01)。上述结果表明,同一条经络上的足三里(ST36)和丰隆(ST40)对大脑有相似的影响,而另一条经络上的阳陵泉(GB37)与足三里(ST36)和丰隆(ST40)有完全不同的影响。本文的结果从脑电图的角度解释了刺激足三里(ST36)和丰隆(ST40)可治疗相似疾病的原因,也说明了刺激阳陵泉(GB37)对大脑的影响与足三里(ST36)和丰隆(ST40)有显著差异。