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1994 - 2003年得克萨斯州男性监狱囚犯中与丙型肝炎病毒(HCV)相关的死亡率

HCV-related mortality among male prison inmates in Texas, 1994-2003.

作者信息

Harzke Amy J, Baillargeon Jacques G, Kelley Michael F, Diamond Pamela M, Goodman Karen J, Paar David P

机构信息

Department of Preventive Medicine and Community Health and the Correctional Managed Care Division, University of Texas Medical Branch, Galveston, Texas 77555, USA.

出版信息

Ann Epidemiol. 2009 Aug;19(8):582-9. doi: 10.1016/j.annepidem.2009.03.009. Epub 2009 May 13.

Abstract

PURPOSE

The prevalence of hepatitis C virus (HCV) infection is high among adult incarcerated populations, but HCV-related mortality data are lacking. The study purpose was to assess HCV-related mortality over time and across racial/ethnic categories from 1994 through 2003 among male prisoners in the Texas Department of Criminal Justice (TDCJ).

METHODS

TDCJ decedent data were linked with Texas Vital Statistics multiple-cause-of-death data. Crude annual HCV death rates, age- and race-adjusted summary rates, and average annual percent changes were estimated. The proportion of deaths due to chronic liver disease/cirrhosis, liver cancer, hepatitis B, and HIV for which HCV was identified as an intervening or contributing cause of death was calculated.

RESULTS

Among Texas male prisoners, HCV death rates were high and increased over the 10-year study period by an average 21% annually, with the largest increase occurring among Hispanic prisoners. HCV was identified as an intervening or contributing cause of death in 15% of chronic liver disease/cirrhosis deaths, 33% of liver cancer deaths, 81% of hepatitis B deaths, and 7% of HIV deaths.

CONCLUSIONS

Because HCV-related deaths among Texas male prisoners are high and increasing, particularly among Hispanics, targeted prevention, screening, and treatment of HCV infections should be among the priorities of U.S. correctional healthcare systems.

摘要

目的

丙型肝炎病毒(HCV)感染在成年在押人群中普遍存在,但缺乏与HCV相关的死亡率数据。本研究的目的是评估1994年至2003年期间,得克萨斯州刑事司法部(TDCJ)男性囚犯中与HCV相关的死亡率随时间变化情况以及不同种族/族裔间的差异。

方法

将TDCJ的死亡数据与得克萨斯州生命统计多死因数据相链接。估算了HCV的年度粗死亡率、年龄和种族调整后的汇总率以及年均变化百分比。计算了慢性肝病/肝硬化、肝癌、乙型肝炎和HIV导致的死亡中,HCV被确定为中间或促成死因的比例。

结果

在得克萨斯州男性囚犯中,HCV死亡率很高,在10年研究期内平均每年增加21%,其中西班牙裔囚犯的增幅最大。在15%的慢性肝病/肝硬化死亡、33%的肝癌死亡、81%的乙型肝炎死亡和7%的HIV死亡中,HCV被确定为中间或促成死因。

结论

由于得克萨斯州男性囚犯中与HCV相关的死亡人数众多且呈上升趋势,尤其是在西班牙裔中,针对性的HCV感染预防、筛查和治疗应成为美国惩教医疗系统的工作重点之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0813/2857775/0a6eccf9c445/nihms-190489-f0001.jpg

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