• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
[Evolution of techniques for preparation of labile blood products (LBP): pathogen inactivation in LBP].[不稳定血液制品（LBP）制备技术的演变：LBP中的病原体灭活]
Transfus Clin Biol. 2009 May;16(2):179-89. doi: 10.1016/j.tracli.2009.03.022. Epub 2009 May 13.
2
[Photochemical inactivation of pathogens in platelets and plasma: five years of clinical use in routine and hemovigilance. Towards a change of paradigm in transfusion safety].[血小板和血浆中病原体的光化学灭活：在常规和血液警戒中的五年临床应用。迈向输血安全范式的转变]
Transfus Clin Biol. 2011 Apr;18(2):53-61. doi: 10.1016/j.tracli.2011.02.023. Epub 2011 Apr 6.
3
[Techniques of preparation and indications of labile blood products].[不稳定血液制品的制备技术与适应证]
Transfus Clin Biol. 2011 Apr;18(2):250-61. doi: 10.1016/j.tracli.2011.02.022. Epub 2011 Apr 6.
4
Implementation of the INTERCEPT Blood System for Platelets into routine blood bank manufacturing procedures: evaluation of apheresis platelets.将血小板的INTERCEPT血液系统应用于常规血库制造程序：单采血小板的评估
Vox Sang. 2004 May;86(4):239-45. doi: 10.1111/j.0042-9007.2004.00419.x.
5
Effect of pathogen inactivation on the storage lesion in red cells and platelet concentrates.病原体灭活对红细胞和血小板浓缩物储存损伤的影响。
Transfus Apher Sci. 2011 Aug;45(1):75-84. doi: 10.1016/j.transci.2011.06.006. Epub 2011 Jul 22.
6
Biomolecular Consequences of Platelet Pathogen Inactivation Methods.血小板病原体失活方法的生物分子后果。
Transfus Med Rev. 2019 Jan;33(1):29-34. doi: 10.1016/j.tmrv.2018.06.002. Epub 2018 Jun 27.
7
Inactivation of yellow fever virus in plasma after treatment with methylene blue and visible light and in platelet concentrates following treatment with ultraviolet C light.亚甲蓝和可见光处理后血浆中黄热病病毒的失活和紫外线 C 处理后血小板浓缩物中黄热病病毒的失活。
Transfusion. 2019 Jul;59(7):2223-2227. doi: 10.1111/trf.15332. Epub 2019 May 3.
8
[The quality of platelet concentrates in dependence on storage time before pathogen inactivation].[血小板浓缩物质量与病原体灭活前储存时间的关系]
Pol Merkur Lekarski. 2011 Mar;30(177):187-90.
9
Preserved functional and biochemical characteristics of platelet components prepared with amotosalen and ultraviolet A for pathogen inactivation.采用氨甲喋呤和长波紫外线对血小板成分进行病原体灭活处理，可保持其功能和生化特性。
Transfusion. 2013 Jun;53(6):1187-200. doi: 10.1111/j.1537-2995.2012.03923.x. Epub 2012 Oct 15.
10
Inactivation of three emerging viruses - severe acute respiratory syndrome coronavirus, Crimean-Congo haemorrhagic fever virus and Nipah virus - in platelet concentrates by ultraviolet C light and in plasma by methylene blue plus visible light.经紫外线 C 照射灭活血小板浓缩液中的三种新兴病毒 - 严重急性呼吸综合征冠状病毒、克里米亚-刚果出血热病毒和尼帕病毒 - 以及经亚甲基蓝联合可见光灭活血浆中的上述三种病毒。
Vox Sang. 2020 Apr;115(3):146-151. doi: 10.1111/vox.12888. Epub 2020 Jan 12.

引用本文的文献

1
Health Technology Assessment of pathogen reduction technologies applied to plasma for clinical use.应用于临床用血制品的病原体灭活技术的卫生技术评估。
Blood Transfus. 2016 Jul;14(4):287-386. doi: 10.2450/2016.0065-16.
2
Main Properties of the THERAFLEX MB-Plasma System for Pathogen Reduction.用于病原体灭活的THERAFLEX MB-血浆系统的主要特性
Transfus Med Hemother. 2011;38(1):55-64. doi: 10.1159/000323786. Epub 2011 Jan 27.
3
[Photochemical inactivation of pathogens in platelets and plasma: five years of clinical use in routine and hemovigilance. Towards a change of paradigm in transfusion safety].[血小板和血浆中病原体的光化学灭活：在常规和血液警戒中的五年临床应用。迈向输血安全范式的转变]
Transfus Clin Biol. 2011 Apr;18(2):53-61. doi: 10.1016/j.tracli.2011.02.023. Epub 2011 Apr 6.

本文引用的文献

1
The hazards of blood transfusion in historical perspective.历史视角下输血的风险。
Blood. 2008 Oct 1;112(7):2617-26. doi: 10.1182/blood-2008-07-077370.
2
The six questions of pathogen reduction technology: an overview of current opinions.病原体灭活技术的六个问题：当前观点概述
Transfus Apher Sci. 2008 Aug;39(1):51-7. doi: 10.1016/j.transci.2008.05.007. Epub 2008 Jul 9.
3
Pathogen reduction of blood components.血液成分的病原体灭活
Transfus Apher Sci. 2008 Aug;39(1):75-82. doi: 10.1016/j.transci.2008.05.003. Epub 2008 Jul 3.
4
Photochemical inactivation with amotosalen and long-wavelength ultraviolet light of Plasmodium and Babesia in platelet and plasma components.用阿莫沙生和长波长紫外线对血小板及血浆成分中的疟原虫和巴贝斯虫进行光化学灭活。
Transfusion. 2008 Aug;48(8):1676-84. doi: 10.1111/j.1537-2995.2007.01762.x. Epub 2008 May 22.
5
Proceedings of a Consensus Conference: pathogen inactivation-making decisions about new technologies.共识会议纪要：病原体灭活——关于新技术的决策
Transfus Med Rev. 2008 Jan;22(1):1-34. doi: 10.1016/j.tmrv.2007.09.001.
6
Pathogen inactivation: making decisions about new technologies. Report of a consensus conference.病原体灭活：关于新技术的决策。共识会议报告。
Transfusion. 2007 Dec;47(12):2338-47. doi: 10.1111/j.1537-2995.2007.01512.x.
7
Pathogen inactivation: a new paradigm for blood safety.病原体灭活：血液安全的新范式。
Transfusion. 2007 Dec;47(12):2180-4. doi: 10.1111/j.1537-2995.2007.01539.x.
8
Potential and limitation of UVC irradiation for the inactivation of pathogens in platelet concentrates.紫外线C照射对灭活血小板浓缩物中病原体的潜力与局限性
Transfusion. 2008 Feb;48(2):304-13. doi: 10.1111/j.1537-2995.2007.01524.x. Epub 2007 Nov 19.
9
Pathogen inactivation of Trypanosoma cruzi in plasma and platelet concentrates using riboflavin and ultraviolet light.使用核黄素和紫外线对血浆及浓缩血小板中的克氏锥虫进行病原体灭活
Transfus Apher Sci. 2007 Oct;37(2):131-7. doi: 10.1016/j.transci.2007.07.002. Epub 2007 Oct 22.
10
Coagulation function in fresh-frozen plasma prepared with two photochemical treatment methods: methylene blue and amotosalen.两种光化学处理方法（亚甲蓝和阿莫沙林）制备的新鲜冰冻血浆中的凝血功能。
Transfusion. 2008 Jan;48(1):108-17. doi: 10.1111/j.1537-2995.2007.01488.x. Epub 2007 Sep 27.

[不稳定血液制品（LBP）制备技术的演变：LBP中的病原体灭活]

[Evolution of techniques for preparation of labile blood products (LBP): pathogen inactivation in LBP].

作者信息

Naegelen C, Isola H, Dernis D, Maurel J-P, Tardivel R, Bois S, Vignoli C, Cazenave J-P

机构信息

EFS Bourgogne-Franche-Comté, 25000 Besançon, France.

出版信息

Transfus Clin Biol. 2009 May;16(2):179-89. doi: 10.1016/j.tracli.2009.03.022. Epub 2009 May 13.

DOI:10.1016/j.tracli.2009.03.022
PMID:19443252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7110575/
Abstract

The techniques for inactivation of pathogens in labile blood products (LBP) would appear to be the new strategy which will permit us to increase transfusion safety in the face of the risks of transmission of pathogenic agents by LBP. Various methods are in the course of development or already validated and used in France. The latter only apply however to plasma or platelet concentrates. The mechanisms of action and the efficacy of inactivation and attenuation of pathogenic agents vary with the different techniques. Each of these constitutes a preparative procedure composed of unit steps which have to be fully mastered in order to ensure the quality and transfusion efficacy of the treated product.

摘要

使不稳定血液制品（LBP）中的病原体失活的技术似乎是一种新策略，它将使我们能够在面对LBP传播病原体风险的情况下提高输血安全性。各种方法正在研发中，或已在法国得到验证并使用。然而，后者仅适用于血浆或血小板浓缩物。病原体失活和减毒的作用机制及效果因不同技术而异。这些技术中的每一种都构成一个由单元步骤组成的制备程序，为确保处理后产品的质量和输血效果，必须全面掌握这些步骤。