Milsom Ian
Department of Obstetrics and Gynecology, Sahlgrenska Academy at Gothenburg University, Sahlgrenska University Hospital, Gothenburg, Sweden.
Curr Opin Urol. 2009 Jul;19(4):337-41. doi: 10.1097/MOU.0b013e32832b659d.
To summarize recent population-based literature on the prevalence and consequences of urinary incontinence and overactive bladder (OAB) symptoms in women and describe our present knowledge regarding known risk factors.
The prevalence of urinary incontinence in women ranged from 5 to 69%, with most studies reporting a prevalence of any urinary incontinence in the range of 25-45%. In a longitudinal population study in which women were followed for 16 years, the overall prevalence of urinary incontinence increased from 15 to 28%, and the incidence rate of urinary incontinence was 21%, whereas the corresponding remission rate was 34%. Increasing evidence is now available regarding a genetic component in the cause of stress urinary incontinence. The reported prevalence of OAB in women varied between 7.7 and 31.3%, and in general, prevalence rates increased with age. In a longitudinal study, the prevalence of OAB, nocturia and daytime micturition frequency of eight or more times per day increased by 9, 20 and 3%, respectively, in a cohort of women followed from 1991 to 2007. The incidence of OAB was 20%, and the corresponding remission rate was 43%.
Urinary incontinence and OAB are highly prevalent conditions. The cost of illness for urinary incontinence and OAB is a substantial economic and human burden and is likely to increase further in the future, highlighting the need for effective forms of management.
总结近期基于人群的关于女性尿失禁和膀胱过度活动症(OAB)症状的患病率及后果的文献,并描述我们目前对已知危险因素的认识。
女性尿失禁的患病率在5%至69%之间,大多数研究报告任何类型尿失禁的患病率在25%至45%之间。在一项对女性进行了16年随访的纵向人群研究中,尿失禁的总体患病率从15%上升至28%,尿失禁的发病率为21%,而相应的缓解率为34%。现在有越来越多的证据表明压力性尿失禁的病因中有遗传因素。报告的女性OAB患病率在7.7%至31.3%之间,一般来说,患病率随年龄增长而增加。在一项纵向研究中,1991年至2007年随访的一组女性中,OAB、夜尿症和白天排尿频率每天8次或更多次的患病率分别增加了9%、20%和3%。OAB的发病率为20%,相应的缓解率为43%。
尿失禁和OAB是高度普遍的病症。尿失禁和OAB的疾病成本是巨大的经济和人力负担,且未来可能会进一步增加,这凸显了有效管理形式的必要性。