在一位患有多巴反应性肌张力障碍（Segawa 综合征）的患者中进行了无意外电抽搐治疗。
Uneventful electroconvulsive therapy in a patient with dopa-responsive dystonia (Segawa syndrome).
机构信息
ECT Department, University Psychiatric Center, Catholic University of Leuven, Kortenberg, Belgium.
出版信息
J ECT. 2009 Dec;25(4):284-6. doi: 10.1097/YCT.0b013e3181a744da.
BACKGROUND
The Segawa syndrome is an autosomal dominant form of guanosine triphosphate cyclohydrolase deficiency, resulting in decreased dopamine and serotonin levels, typically presenting as a dopa-responsive dystonia.
METHOD
Case presentation of a 56-year-old man with dopa-responsive dystonia, treated with electroconvulsive therapy for a psychotic depression.
RESULTS
Scores on the Inventory of Depressive Symptomatology dropped from 35 before treatment to 3 after the eighth treatment session. Etomidate and succinylcholine were used as anesthetics. Apart from 2 sessions with postictal agitation, the course of electroconvulsive therapy was finished uneventfully. Electroconvulsive therapy and anesthesia had no untoward effects on motor function.
CONCLUSIONS
Electroconvulsive therapy can be administered safely and effectively in a patient with dopa-responsive dystonia (Segawa syndrome).
背景
Segawa 综合征是鸟苷三磷酸环化水解酶缺陷的常染色体显性遗传形式，导致多巴胺和 5-羟色胺水平降低，通常表现为多巴反应性肌张力障碍。
方法
报告一例 56 岁男性多巴反应性肌张力障碍患者，因精神病性抑郁症接受电抽搐治疗。
结果
在第八次治疗后，抑郁症状清单的评分从治疗前的 35 分降至 3 分。使用依托咪酯和琥珀胆碱作为麻醉剂。除了两次电抽搐后出现激越外，电抽搐治疗过程顺利完成。电抽搐治疗和麻醉对运动功能没有不良影响。
结论
电抽搐治疗可安全有效地应用于多巴反应性肌张力障碍（Segawa 综合征）患者。
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