用于评估普通女性人群中临床相关盆腔器官脱垂的预测模型和预后指数。
Prediction model and prognostic index to estimate clinically relevant pelvic organ prolapse in a general female population.
作者信息
Slieker-ten Hove Marijke C Ph, Pool-Goudzwaard Annelies L, Eijkemans Marinus J C, Steegers-Theunissen Regine P M, Burger Curt W, Vierhout Mark E
机构信息
Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.
出版信息
Int Urogynecol J Pelvic Floor Dysfunct. 2009 Sep;20(9):1013-21. doi: 10.1007/s00192-009-0903-0. Epub 2009 May 15.
INTRODUCTION AND HYPOTHESIS
Estimation on prevalence and distribution of pelvic organ prolapse (POP) signs in a general female population is difficult. We therefore developed and validated a prediction model and prognostic instrument.
METHODS
Questionnaires were sent to a general female population (45-85 years). A random sample underwent vaginal examination for POP (POPQ). A prediction model was developed using multivariate analysis and validated in a subgroup of participants.
RESULTS
Positive questionnaire-response rate was 46.8% (1,397 of 2,979). From the questionnaire group, 649 women were vaginally examined (46.5%). Prevalence of clinically relevant POP was 21%. Multivariate analysis demonstrated significantly higher odds ratios on the report of vaginal bulging, parity > or = 2 and a mother with POP. The receiver operating characteristic curve showed areas under the curve of 0.672 and 0.640.
CONCLUSIONS
The prevalence of POP at or beyond the hymen could be estimated in a general female population using our prediction model with 17 questions and our POP score chart with eight questions.
引言与假设
在普通女性人群中估计盆腔器官脱垂（POP）体征的患病率和分布情况较为困难。因此，我们开发并验证了一种预测模型和预后工具。
方法
向普通女性人群（45 - 85岁）发放问卷。随机抽取一部分人进行盆腔器官脱垂的阴道检查（盆腔器官脱垂定量分期系统）。使用多变量分析开发了一种预测模型，并在一部分参与者中进行了验证。
结果
问卷的阳性回复率为46.8%（2979人中的1397人）。在问卷组中，649名女性接受了阴道检查（46.5%）。临床相关盆腔器官脱垂的患病率为21%。多变量分析表明，阴道膨出报告、产次≥2以及母亲患有盆腔器官脱垂的比值比显著更高。受试者工作特征曲线显示曲线下面积为0.672和0.640。
结论
使用我们的包含17个问题的预测模型和包含8个问题的盆腔器官脱垂评分表，可以在普通女性人群中估计处女膜及处女膜以上盆腔器官脱垂的患病率。
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