Bégué Pierre
L'Académie nationale de médecine.
Bull Acad Natl Med. 2008 Oct;192(7):1339-47.
Much progress has been made in the past two decades in the diagnosis and management of sickle-cell disease. Clinical, pathophysiological and therapeutic studies have given rise to national procedures for all patients. Life expectancy has improved dramatically in industrialized countries, and the number of sickle-cell patients reaching adulthood is growing. Neonatal diagnosis began in France in 1995 and is crucial for early prevention. Crisis management and long-term surveillance both require dedicated drepanocytosis centers for children and for adults.
在过去二十年中，镰状细胞病的诊断和管理取得了很大进展。临床、病理生理学和治疗研究催生了针对所有患者的国家程序。在工业化国家，预期寿命显著提高，成年镰状细胞病患者的数量也在增加。1995年法国开始了新生儿诊断，这对早期预防至关重要。危机管理和长期监测都需要为儿童和成人设立专门的镰状细胞病中心。
