Calvo María Isabel
Dipartamento Farmacia y Tecnología Farmacéutica (Facultad de Farmacia), University of Navarra, 31008, Pamplona, Spain.
Fitoterapia. 2009 Oct;80(7):394-8. doi: 10.1016/j.fitote.2009.05.010. Epub 2009 May 14.
Three new homoisoflavanones, namely ledebourin A (1), ledebourin B (2) and ledebourin C (3) were isolated from the bulbs of Ledebouria floribunda. Their structures were elucidated on the basis of detail spectroscopic analyses. This is the first report of this type of homoisoflavanones. Ledebourin B (2) and ledebourin C (3) exhibited potent antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging compared to the positive controls, the well-known antioxidant BHT and BHA.
从多花独尾草的鳞茎中分离出三种新的高异黄酮,即列当黄素A(1)、列当黄素B(2)和列当黄素C(3)。通过详细的光谱分析确定了它们的结构。这是此类高异黄酮的首次报道。与阳性对照、著名抗氧化剂丁基羟基甲苯(BHT)和丁基羟基茴香醚(BHA)相比,列当黄素B(2)和列当黄素C(3)在2,2-二苯基-1-苦基肼(DPPH)自由基清除实验中表现出较强的抗氧化活性。