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感染性主动脉瘤的血管腔内修复术。

Endovascular repair of mycotic aortic aneurysms.

作者信息

Sörelius Karl, Mani Kevin, Björck Martin, Nyman Rickard, Wanhainen Anders

机构信息

Department of Surgery, Section of Vascular Surgery, Uppsala University Hospital, Uppsala, Sweden.

出版信息

J Vasc Surg. 2009 Aug;50(2):269-74. doi: 10.1016/j.jvs.2009.01.001. Epub 2009 May 15.

Abstract

PURPOSE

We report our single-center experience of early and midterm outcome after endovascular repair of mycotic aortic aneurysms (MAA).

METHODS

Case records were retrospectively reviewed of 11 patients who underwent endovascular repair of 13 MAAs between 2000 and 2007. The aneurysms were localized in the aortic arch in 1 patient, descending thoracic aorta in 4, suprarenal abdominal aorta in 3, and infrarenal abdominal aorta in 5.

RESULTS

Mean follow-up was 27 months. A bleeding aortoesophageal fistula resulted in one in-hospital death <or=30 days. Three patients died later: one each of sepsis, stent migration that caused intestinal ischemia, and an unknown cause. Two patients had recurrent sepsis postoperatively but no vascular complications, two had elevated inflammatory markers during follow-up but were asymptomatic, and three patients had an uneventful follow-up.

CONCLUSIONS

Endovascular treatment for MAA was feasible, with acceptable perioperative mortality and midterm outcome in this single-center case series. Recurrent sepsis and late relapse with a second MAA occurred, indicating the need of long-term antibiotic therapy and follow-up, as well as the possible need for secondary open repair in selected cases. Further research is warranted to evaluate long-term outcome.

摘要

目的

我们报告了在本单中心对感染性主动脉瘤(MAA)进行血管腔内修复后的早期和中期结果的经验。

方法

回顾性分析了2000年至2007年间11例接受13例MAA血管腔内修复患者的病例记录。动脉瘤位于主动脉弓1例,胸降主动脉4例,肾上腹主动脉3例,肾下腹主动脉5例。

结果

平均随访27个月。1例患者在住院<或=30天内死于主动脉食管瘘出血。3例患者随后死亡:分别死于败血症、支架移位导致肠缺血和不明原因。2例患者术后反复发生败血症但无血管并发症,2例在随访期间炎症标志物升高但无症状,3例患者随访顺利。

结论

在本单中心病例系列中,MAA的血管腔内治疗是可行的,围手术期死亡率和中期结果可接受。发生了反复败血症和第二个MAA的晚期复发,表明需要长期抗生素治疗和随访,以及在某些情况下可能需要二次开放修复。有必要进一步研究以评估长期结果。

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