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恶性肿瘤的电解质并发症

Electrolyte complications of malignancy.

作者信息

Kacprowicz Robert F, Lloyd Jeremy D

机构信息

San Antonio Uniformed Services Health Education Consortium Residency in Emergency Medicine, San Antonio, TX, USA.

出版信息

Emerg Med Clin North Am. 2009 May;27(2):257-69. doi: 10.1016/j.emc.2009.01.007.

DOI:10.1016/j.emc.2009.01.007
PMID:19447310
Abstract

A thorough working knowledge of the diagnosis and treatment of life-threatening electrolyte abnormalities in cancer patients, especially hyponatremia, hypoglycemia, and hypercalcemia, is essential to the successful practice of emergency medicine. Although most minor abnormalities have no specific treatment, severe clinical manifestations of several notable electrolytes occur with significant frequency in the setting of malignancy. The treatment of life-threatening electrolyte abnormalities is reviewed here. Promising future treatments directed at the underlying physiology are also introduced.

摘要

全面掌握癌症患者危及生命的电解质紊乱(尤其是低钠血症、低血糖症和高钙血症)的诊断和治疗方法,对于成功开展急诊医学至关重要。虽然大多数轻微的电解质异常无需特殊治疗,但在恶性肿瘤患者中,几种显著电解质的严重临床表现却相当常见。本文将对危及生命的电解质紊乱的治疗进行综述。同时也将介绍针对潜在生理机制的有前景的未来治疗方法。

相似文献

1
Electrolyte complications of malignancy.恶性肿瘤的电解质并发症
Emerg Med Clin North Am. 2009 May;27(2):257-69. doi: 10.1016/j.emc.2009.01.007.
2
Electrolyte complications of malignancy.恶性肿瘤的电解质并发症。
Hematol Oncol Clin North Am. 2010 Jun;24(3):553-65. doi: 10.1016/j.hoc.2010.03.007.
3
Therapeutic approach to electrolyte emergencies.电解质急症的治疗方法。
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Electrolyte Disturbances in Critically Ill Cancer Patients: An Endocrine Perspective.危重症癌症患者的电解质紊乱:内分泌学视角
J Intensive Care Med. 2018 Mar;33(3):147-158. doi: 10.1177/0885066617706650. Epub 2017 May 24.
5
Fluid and electrolyte abnormalities.液体和电解质异常。
Crit Care Clin. 2001 Jul;17(3):503-29. doi: 10.1016/s0749-0704(05)70197-4.
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Causes and mechanisms of acid-base and electrolyte abnormalities in cancer patients.癌症患者酸碱及电解质异常的原因和机制。
Eur J Intern Med. 2008 Jan;19(1):1-7. doi: 10.1016/j.ejim.2007.04.016. Epub 2007 Jul 23.
7
[Water-electrolyte imbalance: physiopathology, diagnosis and treatment].
Rev Prat. 2008 Sep 30;58(14):1601-11.
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Life-threatening fluid and electrolyte abnormalities associated with cancer.
Crit Care Clin. 1988 Jan;4(1):81-105.
9
[Electrolyte metabolism and emergency].[电解质代谢与急症]
Gan To Kagaku Ryoho. 1983 Feb;10(2 Pt):198-203.
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[Hyperhydration. Etiology, physiopathology, diagnosis, principles of treatment].
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Prognostic value of normal sodium levels in patients with metastatic renal cell carcinoma receiving tyrosine kinase inhibitors.接受酪氨酸激酶抑制剂治疗的转移性肾细胞癌患者正常钠水平的预后价值
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Hyponatremia as a powerful prognostic predictor for Japanese patients with clear cell renal cell carcinoma treated with a tyrosine kinase inhibitor.
低钠血症作为日本透明细胞肾细胞癌患者接受酪氨酸激酶抑制剂治疗的有力预后预测指标。
Int J Clin Oncol. 2015 Apr;20(2):351-7. doi: 10.1007/s10147-014-0713-3. Epub 2014 Jun 4.
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Paraneoplastic syndromes: an approach to diagnosis and treatment.副肿瘤综合征:一种诊断和治疗方法。
Mayo Clin Proc. 2010 Sep;85(9):838-54. doi: 10.4065/mcp.2010.0099.
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Hyponatremia as a prognostic and predictive factor in metastatic renal cell carcinoma.低钠血症作为转移性肾细胞癌的预后和预测因素。
Br J Cancer. 2010 Mar 2;102(5):867-72. doi: 10.1038/sj.bjc.6605563. Epub 2010 Feb 9.