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单次脊髓麻醉、腰麻-硬膜外联合麻醉及硬膜外容量扩张用于择期剖宫产的随机对照研究

Single-shot spinal anaesthesia, combined spinal-epidural and epidural volume extension for elective caesarean section: a randomized comparison.

作者信息

Tyagi A, Girotra G, Kumar A, Kumar S, Sethi A Kumar, Mohta M

机构信息

Department of Anaesthesiology & Critical Care, University College of Medical Sciences & Guru Teg Bahadur Hospital, Shahadra, Delhi-110095, India.

出版信息

Int J Obstet Anesth. 2009 Jul;18(3):231-6. doi: 10.1016/j.ijoa.2009.01.007. Epub 2009 May 17.

Abstract

BACKGROUND

Single-shot spinal and combined spinal-epidural block, with or without epidural volume extension, can be used for caesarean section. There is no trial comparing their block characteristics and adverse effects under identical conditions.

METHODS

60 ASA I or II parturients with gestational age 37 weeks or more, scheduled for elective caesarean section under regional anaesthesia, were included in the trial. Women were randomized to three groups: group SSS: single-shot spinal; group CSE: combined spinal-epidural; group EVE: epidural volume extension of a combined spinal-epidural. Intrathecal injection was identical in the three groups (0.5% hyperbaric bupivacaine 9 mg with fentanyl 10 microg) and was injected via a 25-gauge pencil-point spinal needle, either as a single-shot spinal or through the spinal needle of the needle-through-needle CSE set. In group EVE, 5 mL of normal saline was injected through the epidural catheter. All blocks were performed with the women sitting. Haemodynamic parameters and block characteristics were assessed.

RESULTS

The onset of maximum sensory and motor block was significantly faster in the SSS group than in the other two. Extent and duration of sensory and motor block and the incidence of adverse effects were similar in the three groups (P>0.05).

CONCLUSIONS

Intrathecal block is similar in extent and duration whether given as a single-shot spinal or a combined spinal-epidural with or without epidural volume extension when performed for elective caesarean section using hyperbaric bupivacaine in the sitting position.

摘要

背景

单次脊麻和腰麻-硬膜外联合阻滞,无论是否进行硬膜外容量扩充,均可用于剖宫产。尚无试验在相同条件下比较它们的阻滞特征和不良反应。

方法

60例年龄37周及以上、拟在区域麻醉下择期行剖宫产的ASA I或II级产妇纳入试验。将产妇随机分为三组:SSS组:单次脊麻;CSE组:腰麻-硬膜外联合阻滞;EVE组:腰麻-硬膜外联合阻滞并进行硬膜外容量扩充。三组的鞘内注射相同(0.5%重比重布比卡因9 mg加芬太尼10 μg),通过25G笔尖式脊麻针注射,要么作为单次脊麻,要么通过针内针腰麻-硬膜外联合阻滞套件的脊麻针注射。在EVE组,通过硬膜外导管注入5 mL生理盐水。所有阻滞均在产妇坐位时进行。评估血流动力学参数和阻滞特征。

结果

SSS组最大感觉和运动阻滞的起效明显快于其他两组。三组感觉和运动阻滞的范围、持续时间及不良反应发生率相似(P>0.05)。

结论

在坐位使用重比重布比卡因进行择期剖宫产时,无论是单次脊麻还是腰麻-硬膜外联合阻滞(无论是否进行硬膜外容量扩充),鞘内阻滞的范围和持续时间相似。

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