Krouwer H G, Vollmerhausen J, White J, Prados M D
Department of Neurological Surgery, School of Medicine, University of California, San Francisco.
Neurosurgery. 1991 Oct;29(4):612-6. doi: 10.1097/00006123-199110000-00024.
A case is reported in which a desmoplastic medulloblastoma metastasized to the pancreas and to the surrounding soft tissues but did not recur locally or disseminate within the central nervous system. Multidrug chemotherapy and local radiation therapy resulted in a complete remission. In all four previously reported cases of medulloblastoma metastasizing to the pancreas, the diagnosis was not made until the postmortem examination, and all of these patients also had extensive metastases in other organ systems. Modification of the Weiss criteria defining extraneural metastases from tumors of the central nervous system is suggested.
报告了1例促结缔组织增生性髓母细胞瘤转移至胰腺及周围软组织,但未在局部复发或在中枢神经系统内播散的病例。多药化疗和局部放疗导致完全缓解。在之前报道的所有4例髓母细胞瘤转移至胰腺的病例中,均直到尸检时才作出诊断,并且所有这些患者在其他器官系统中也有广泛转移。建议对定义中枢神经系统肿瘤神经外转移的魏斯标准进行修订。