Sam M, Gutmann L, Schochet S S, Doshi H
Department of Neurology, West Virginia University, Morgantown 26506.
Neurology. 1991 Nov;41(11):1831-3. doi: 10.1212/wnl.41.11.1831.
A 50-year-old woman with a progressive neurologic illness clinically resembling amyotrophic lateral sclerosis had Pick's disease verified at autopsy. This case represents another example of Pick's disease in which the early manifestations were not those of dementia. This patient also showed some unusual histopathologic features, including degeneration of the substantia nigra and occasional "compound Pick bodies."
一名50岁患有进行性神经系统疾病的女性，临床表现类似肌萎缩侧索硬化症，尸检证实患有皮克病。该病例是皮克病的又一实例，其早期表现并非痴呆症状。该患者还呈现出一些不寻常的组织病理学特征，包括黑质变性和偶尔出现的“复合型皮克小体”。
