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播散性结核分枝杆菌治疗开始后发生的严重噬血细胞综合征:病例报告及文献综述

Severe hemophagocytic syndrome developing after treatment initiation for disseminated Mycobacterium tuberculosis: case report and literature review.

作者信息

Balkis Maher M, Bazzi Lama, Taher Ali, Salem Ziad, Uthman Imad, Kanj Nadim, Boulos Fouad I, Kanj Souha S

机构信息

Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Scand J Infect Dis. 2009;41(6-7):535-7. doi: 10.1080/00365540902978075.

Abstract

We describe a case of a young male with disseminated tuberculosis and severe secondary hemophagocytic syndrome. He presented with symptoms of tuberculosis and Mycobacterium tuberculosis was diagnosed. Later, while on anti-tuberculous treatment, he developed pancytopenia and bone marrow aspirate showed large macrophages with increased phagocytosis of mature and immature blood elements typical of hemophagocytic syndrome.

摘要

我们描述了一例患有播散性肺结核和严重继发性噬血细胞综合征的年轻男性病例。他出现了肺结核症状,诊断为结核分枝杆菌感染。后来,在接受抗结核治疗期间,他出现了全血细胞减少,骨髓穿刺显示有大量巨噬细胞,对成熟和未成熟血细胞的吞噬作用增强,这是噬血细胞综合征的典型表现。

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