Paulo Luciana T S P, Terreri Maria Teresa R A, Barbosa Cássia Maria P, Len Claudio Arnaldo, Hilário Maria Odete E
Setor de Reumatologia Pediátrica, Disciplina de Alergia, Imunologia clínica e Reumatologia do Departamento de Pediatria da Universidade Federal de São Paulo - Escola Paulista de Medicina.
Acta Reumatol Port. 2009 Jan-Mar;34(1):66-70.
To assess the frequency and characteristics of clinical manifestations of rheumatic fever in children and adolescents according to the age of onset of the disease.
We evaluated in a retrospective cohort study the clinical and demographic data of rheumatic fever patients followed at our service for at least 6 months and who attended 2 or more visits.
The charts of 202 children and adolescents with rheumatic fever were evaluated and divided into 3 groups according to the age of the first episode of rheumatic fever: group 1- patients under 5 years old (8 [4%]), group 2- patients between 5 and 9 years (84 [42%]) and group 3 patients with 10 years old or older (110 [54%]). The mean follow-up was 4.1 years. Carditis occurred in 24%, 42% and 50%; arthritis in 75%, 71% and 69% and chorea in 25%, 37% and 34% in groups 1, 2 and 3 respectively. There was no statistical difference between the groups in relation to the frequency of such events and of severe carditis, however we observed lower numeric frequency of carditis and Sydenham chorea in children younger than 5 years.
Rheumatic fever, although less frequent, can be found in children under 5 years with no significant difference in relation to the frequency or severity of clinical manifestations.
根据发病年龄评估儿童和青少年风湿热临床表现的频率及特征。
我们在一项回顾性队列研究中评估了在我们科室随访至少6个月且就诊2次或更多次的风湿热患者的临床和人口统计学数据。
对202例儿童和青少年风湿热患者的病历进行了评估，并根据风湿热首次发作的年龄分为3组：第1组为5岁以下患者（8例[4%]），第2组为5至9岁患者（84例[42%]），第3组为10岁及以上患者（110例[54%]）。平均随访时间为4.1年。第1、2和3组中心脏炎的发生率分别为24%、42%和50%；关节炎的发生率分别为75%、71%和69%；舞蹈病的发生率分别为25%、37%和34%。这些事件及严重心脏炎的发生率在各组之间无统计学差异，然而我们观察到5岁以下儿童心脏炎和 Sydenham 舞蹈病的数字频率较低。
风湿热在5岁以下儿童中虽较少见，但临床表现的频率或严重程度无显著差异。
