Könönen E, Asikainen S, Alaluusua S, Könönen M, Summanen P, Kanervo A, Jousimies-Somer H
Department of Periodontology, University of Helsinki.
Oral Microbiol Immunol. 1991 Apr;6(2):119-22. doi: 10.1111/j.1399-302x.1991.tb00463.x.
A complete loss of teeth may eliminate some pathogenic bacteria for lack of a suitable habitat for colonization. The occurrence of Actinobacillus actinomycetemcomitans, black-pigmented Bacteroides, mutans streptococci, lactobacilli and yeasts was investigated in 51 edentulous subjects with complete denture(s); mean age 74 years (range 44-92 years). None of the subjects had received antibiotics during the preceding 6 months. Four swab samples per subject were taken from the fitting surface of the upper denture, from the palate, buccal mucosae and dorsum of the tongue. At least 0.5 ml of stimulated saliva was collected into a sterile tube. The samples were cultivated aerobically and anaerobically using nonselective and selective media. A. actinomycetemcomitans was not found in any of the samples. Black-pigmented Bacteroides were found in 49 (96%) and yeasts in 25 (49%) of the subjects. Of the 49 saliva samples, 41 (84%) yielded mutans streptococci and 45 (92%) lactobacilli. In contrast to black-pigmented Bacteroides, mutans streptococci and lactobacilli, A. actinomycetemcomitans may not belong to the normal oral flora of edentulous subjects wearing dentures.
牙齿全部缺失可能会因缺乏适宜的定植栖息地而消除一些病原菌。对51名佩戴全口义齿的无牙颌患者（平均年龄74岁，范围44 - 92岁）进行了伴放线放线杆菌、产黑色素拟杆菌、变形链球菌、乳酸杆菌和酵母菌的检测。所有患者在之前6个月内均未使用过抗生素。每位患者从全口义齿的贴合面、腭部、颊黏膜和舌背采集4份拭子样本。至少0.5毫升刺激唾液收集到无菌试管中。样本分别在需氧和厌氧条件下使用非选择性和选择性培养基进行培养。所有样本中均未发现伴放线放线杆菌。49名（96%）患者检测出产黑色素拟杆菌，25名（49%）患者检测出酵母菌。在49份唾液样本中，41份（84%）检测出变形链球菌，45份（92%）检测出乳酸杆菌。与产黑色素拟杆菌、变形链球菌和乳酸杆菌不同，伴放线放线杆菌可能不属于佩戴义齿的无牙颌患者的正常口腔菌群。
