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不完全川崎病后继发全身型幼年特发性关节炎,类似川崎病。

Incomplete Kawasaki syndrome followed by systemic onset-juvenile idiopathic arthritis mimicking Kawasaki syndrome.

机构信息

Department of Pediatric Sciences, Università Cattolica Sacro Cuore, Largo A. Gemelli no. 8, Rome, Italy.

出版信息

Rheumatol Int. 2010 Feb;30(4):535-9. doi: 10.1007/s00296-009-0960-1. Epub 2009 May 20.

DOI:10.1007/s00296-009-0960-1
PMID:19455336
Abstract

A 3-month-old child was first treated for incomplete Kawasaki syndrome with three cycles of intravenous immunoglobulins and aspirin, then with methylprednisolone which led to fever remission. The same child was re-hospitalized after a 10-month-period of well-being for the suspicion of a new episode of Kawasaki syndrome, which appeared to be immunoglobulin-resistant: extensive testing failed to provide an alternative diagnosis of any infectious or infiltrative disease. Diagnosis of systemic onset-juvenile idiopathic arthritis was postulated upon the long persistence of fever and inflammatory signs, which subsided only after starting corticosteroid treatment.

摘要

一个 3 个月大的婴儿最初接受了三个周期的静脉注射免疫球蛋白和阿司匹林治疗不完全川崎病,然后用甲基强的松龙治疗,使发热缓解。10 个月后,该婴儿在身体状况良好的情况下再次住院,怀疑出现新的川崎病发作,该疾病似乎对免疫球蛋白有抵抗作用:广泛的检查未能提供任何感染或浸润性疾病的替代诊断。由于发热和炎症迹象持续存在,在开始皮质类固醇治疗后才消退,因此推测该儿童患有全身型幼年特发性关节炎。

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本文引用的文献

1
Failure to distinguish systemic-onset juvenile idiopathic arthritis from incomplete Kawasaki disease in an infant.婴儿期未能区分全身型幼年特发性关节炎与不完全川崎病。
J Paediatr Child Health. 2007 Oct;43(10):707-9. doi: 10.1111/j.1440-1754.2007.01189.x.
2
Making the diagnosis of systemic lupus erythematosus in children and adolescents.儿童及青少年系统性红斑狼疮的诊断
Lupus. 2007;16(8):546-9. doi: 10.1177/0961203307078068.
3
Mevalonate kinase deficiency and autoinflammatory disorders.甲羟戊酸激酶缺乏症与自身炎症性疾病。
川崎病不完全型合并极高血清铁蛋白及白细胞介素-18 血症 1 例
BMC Pediatr. 2018 Dec 12;18(1):386. doi: 10.1186/s12887-018-1365-7.
4
Serum IL-18 as a potential specific marker for differentiating systemic juvenile idiopathic arthritis from incomplete Kawasaki disease.血清白细胞介素-18作为鉴别全身型幼年特发性关节炎与不完全川崎病的潜在特异性标志物。
Rheumatol Int. 2015 Jan;35(1):81-4. doi: 10.1007/s00296-014-3059-2. Epub 2014 Jun 12.
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Incomplete Kawasaki disease followed by systemic onset juvenile idiopathic arthritis- the diagnostic dilemma.不完全川崎病后继发全身型幼年特发性关节炎——诊断困境。
Indian J Pediatr. 2013 Sep;80(9):783-5. doi: 10.1007/s12098-012-0893-7. Epub 2012 Oct 10.
6
Delayed diagnosis of Kawasaki syndrome and thrombosis of a medium-sized aneurysm of the anterior descending coronary artery: case report and literature review.川崎病合并前降支中段小动脉瘤血栓形成的延迟诊断:病例报告及文献复习。
Rheumatol Int. 2012 Mar;32(3):809-14. doi: 10.1007/s00296-011-1814-1. Epub 2011 Feb 16.
N Engl J Med. 2007 Jun 28;356(26):2671-3. doi: 10.1056/NEJMp078083.
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Pediatric malignancies presenting as a possible infectious disease.表现为可能的感染性疾病的儿科恶性肿瘤。
BMC Infect Dis. 2007 May 22;7:44. doi: 10.1186/1471-2334-7-44.
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Focus on juvenile idiopathic arthritis according to the 2001 Edmonton revised classification from the International League of Associations for Rheumatology: an Italian experience.根据2001年国际风湿病联盟协会(ILAR)埃德蒙顿修订分类法聚焦青少年特发性关节炎:意大利的经验
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The multi-face expression of familial Mediterranean fever in the child.儿童家族性地中海热的多面表现
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Recurrent infections and joint pain.反复感染和关节疼痛。
Allergy Asthma Proc. 2006 Mar-Apr;27(2):164-71.
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Pediatrics. 2005 Jul;116(1):e89-93. doi: 10.1542/peds.2004-2190. Epub 2005 Jun 1.