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梅尼埃病中鼓膜张肌和镫骨肌肌腱切断术

Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease.

作者信息

De Valck C F J, Van Rompaey V, Wuyts E L, Van de Heyning P H

机构信息

Antwerp University Research centre for Equilibrium and Aerospace, Univ. Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital.

出版信息

B-ENT. 2009;5(1):1-6.

Abstract

UNLABELLED

Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease.

OBJECTIVE

In Ménière's disease (MD), when patients have incapacitating vertigo that is resistant to drug treatment, an intratympanic gentamicin application (ITG) is often proposed. Recently, some authors suggested that tenotomy, sectioning of the tensor tympani and stapedius tendons, could be a promising treatment. We examined whether tenotomy (ST) has additional benefit, compared to ITG alone, with respect to tinnitus, vertigo, and quality of life.

METHODOLOGY

We conducted a retrospective survey of the charts of 24 patients with MD who underwent ITG, or ITG plus ST. Baseline data and follow-up assessments were obtained, using the Ménière's Disease Outcomes Questionnaire (MDOQ), the Dizziness Handicap Inventory (DHI), vertigo frequency per month, tinnitus visual analogue scale, and functional level. Failure was determined by the need for an additional procedure.

RESULTS

ITG was performed on 15 patients, and 9 patients underwent ITG plus ST. The procedure was sufficient in 53% of the ITG group and in 22% of the ITG plus ST group. No significant difference was found between the two groups concerning MDOQ scores, DHI, functional level, vertigo frequency, and tinnitus. In the ITG group, we found a significant improvement in number of vertigo attacks and the tinnitus visual analogue scale. In the ITG plus ST group, there was a significant reduction in vertigo attacks, but not in tinnitus.

CONCLUSION

This preliminary study suggests no additional benefit of stapedius and tensor tympani tenotomy in the treatment of Ménière's disease patients.

摘要

未标注

梅尼埃病中鼓膜张肌和镫骨肌肌腱切断术

目的

在梅尼埃病(MD)中,当患者出现对药物治疗无效的致残性眩晕时,常建议进行鼓室内庆大霉素注射(ITG)。最近,一些作者认为切断鼓膜张肌和镫骨肌肌腱可能是一种有前景的治疗方法。我们研究了与单独使用ITG相比,切断术(ST)在耳鸣、眩晕和生活质量方面是否有额外益处。

方法

我们对24例接受ITG或ITG加ST的MD患者的病历进行了回顾性调查。使用梅尼埃病结局问卷(MDOQ)、头晕残障量表(DHI)、每月眩晕频率、耳鸣视觉模拟量表和功能水平获取基线数据和随访评估结果。通过是否需要额外手术来确定治疗失败。

结果

15例患者接受了ITG,9例患者接受了ITG加ST。ITG组53%的患者治疗有效,ITG加ST组为22%。两组在MDOQ评分、DHI、功能水平、眩晕频率和耳鸣方面无显著差异。在ITG组,我们发现眩晕发作次数和耳鸣视觉模拟量表有显著改善。在ITG加ST组,眩晕发作次数显著减少,但耳鸣无改善。

结论

这项初步研究表明,镫骨肌和鼓膜张肌切断术在治疗梅尼埃病患者方面没有额外益处。

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