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救援直升机模拟紧急运输过程中的应激反应:应激激素、生命体征与主观幸福感之间的互相关联

Stress during simulated emergency transportation in a rescue helicopter: cross-correlation between stress hormones, vital functions and subjective well-being.

作者信息

Witzel K, Elzer M, Koch Horst J

机构信息

Paracelsus Private Medical University A-5020 Salzburg Austria.

出版信息

Acta Physiol Hung. 2009 Jun;96(2):221-30. doi: 10.1556/APhysiol.96.2009.2.7.

Abstract

Vital functions and stress hormone levels during simulated emergency helicopter transport in healthy volunteers. Twenty-three volunteers were subjected to a simulated 15 minute rescue helicopter transport. We determined vital functions, ACTH, cortisol and prolactin during the flight and filled in a standardized questionnaire before and after the flight. Data were analysed descriptively, by means of cross tabulation, Spearman rank correlation and cross-correlation technique. During take-off we recorded a significant increase of vital parameters such as heart rate. Prolactin concentration rose slightly after the start. Maximum cortisol and ACTH levels were found before take-off and then they decreased gradually. As expected, ACTH and cortisol cross-correlated significantly without any relevant time lag. Test items showed a feeling of fear and concern before take off. After the flight the volunteers reported having less stress than expected. Particularly, diastolic blood pressure and prolactin levels were markedly associated with questionnaire items such as behaviour of the staff or nausea. Heart rate significantly correlated with anxiety scores. Helicopter transportation induced a marked stress reaction in healthy volunteers, which speaks in favour of smooth transports in modern helicopters and adequate behaviour towards the patient of the staff.

摘要

健康志愿者在模拟紧急直升机运输过程中的生命体征及应激激素水平。23名志愿者接受了一次模拟的15分钟救援直升机运输。我们在飞行过程中测定了生命体征、促肾上腺皮质激素(ACTH)、皮质醇和催乳素,并在飞行前后填写了一份标准化问卷。通过交叉列表、Spearman等级相关和交叉相关技术对数据进行描述性分析。起飞过程中,我们记录到心率等生命体征参数显著增加。飞行开始后催乳素浓度略有上升。皮质醇和ACTH的最高水平出现在起飞前,随后逐渐下降。正如预期的那样,ACTH和皮质醇显著交叉相关,且无任何相关时间延迟。测试项目显示起飞前有恐惧和担忧的感觉。飞行后志愿者报告的压力比预期小。特别是舒张压和催乳素水平与诸如工作人员行为或恶心等问卷项目显著相关。心率与焦虑评分显著相关。直升机运输在健康志愿者中引发了明显的应激反应,这表明现代直升机的平稳运输以及工作人员对患者的适当行为是有利的。

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