Ozdemir Hakan, Tunçbilek Gökhan
Department of Plastic and Reconstructive Surgery, Hacettepe University Medical School, Ankara, Turkey.
J Craniofac Surg. 2009 May;20(3):971-3. doi: 10.1097/SCS.0b013e3181a2e430.
The nose is the most common site for cutaneous malignancies, and metastatic lesions in the skin of the nose are very rare, particularly metastasis of carcinoma of the uterine cervix. We present the fourth patient with carcinoma of the uterine cervix who had cutaneous metastasis to the nose, indicating the dissemination of her carcinoma. The patient had a diagnosis of carcinoma of the uterine cervix labeled as International Federation of Gynecology and Obstetrics stage IIB 30 months ago. She was treated with pelvic chemoradiotherapy. Multiple metastases in both of the lungs were detected by computed tomography of the thorax 1 month ago. In addition, a week later, a lesion on her nose started to appear. With an external nasal incision, the mass was excised with tumor-free borders including a skin island. Unfortunately, the patient died on the eighth postoperative day. This patient showed a very poor prognosis after the appearance of a cutaneous metastasis of the cervical carcinoma, which is often perceived as a preterminal event, generally occurring in the later stages of the illness. The treatment of these conditions is palliative and should ameliorate the mood of the patient.
鼻子是皮肤恶性肿瘤最常见的发病部位,而鼻部皮肤的转移瘤非常罕见,尤其是子宫颈癌的转移。我们报告第四例子宫颈癌患者发生鼻部皮肤转移,提示其癌症已发生播散。该患者30个月前被诊断为国际妇产科联盟(FIGO)IIB期子宫颈癌,接受了盆腔放化疗。1个月前胸部计算机断层扫描(CT)发现双肺多发转移。此外,1周后其鼻部出现一个肿物。通过鼻外切口,完整切除肿物及周边无瘤皮肤组织。不幸的是,患者术后第8天死亡。该患者子宫颈癌出现皮肤转移后预后极差,这通常被视为临终前事件,一般发生在疾病晚期。这些情况的治疗是姑息性的,应改善患者的情绪。