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Antioxidant action of propofol on liver microsomes, mitochondria and brain synaptosomes in the rat.

作者信息

Musacchio E, Rizzoli V, Bianchi M, Bindoli A, Galzigna L

机构信息

Department of Biological Chemistry, University of Padova, Italy.

出版信息

Pharmacol Toxicol. 1991 Jul;69(1):75-7. doi: 10.1111/j.1600-0773.1991.tb00414.x.

Abstract

2,6-Diisopropylphenol (propofol), a new intravenous anaesthetic, has a structure similar to that of butylated hydroxytoluene (BHT). Both compounds inhibit the production of malondialdehyde (MDA) in rat liver mitochondria and microsomes as well as in rat brain synaptosomes treated with lipid peroxidation inducers.

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