Bezborodova S I
Prikl Biokhim Mikrobiol. 1991 May-Jun;27(3):308-29.
The recent discovery of unexpected functional diversity of different RNA molecules and some products of their degradation renewed the interest in ribonucleases. This review mainly presents recent systematized data on animal ribonucleases, including pyrimidine-specific ribonucleases, angiogenin, eosinophil-derived neurotoxin, eosinophil cationic protein, and lectins from frog eggs. The relationship between amino acid sequences and possible pathways of the evolution of this protein superfamily is discussed, as well as properties and primary structures of protein ribonuclease inhibitors.
最近,不同RNA分子及其一些降解产物意外的功能多样性被发现,这重新引发了人们对核糖核酸酶的兴趣。本综述主要介绍了关于动物核糖核酸酶的最新系统数据,包括嘧啶特异性核糖核酸酶、血管生成素、嗜酸性粒细胞衍生神经毒素、嗜酸性粒细胞阳离子蛋白以及蛙卵凝集素。文中讨论了该蛋白质超家族氨基酸序列与可能的进化途径之间的关系,以及蛋白质核糖核酸酶抑制剂的特性和一级结构。