Fernando Hiran C, Murthy Sudish C, Hofstetter Wayne, Shrager Joseph B, Bridges Charles, Mitchell John D, Landreneau Rodney J, Clough Ellen R, Watson Thomas J
Boston University School of Medicine and Department of Cardiothoracic Surgery, Boston Medical Center, Boston, Massachussetts 02118, USA.
Ann Thorac Surg. 2009 Jun;87(6):1993-2002. doi: 10.1016/j.athoracsur.2009.04.032.
The management of Barrett's esophagus with high-grade dysplasia is controversial. The standard of care has traditionally been esophagectomy. However, a number of treatment options aimed at esophageal preservation are increasingly being utilized by many centers. These esophageal-sparing approaches include endoscopic surveillance, mucosal ablation, and endoscopic mucosal resection. In this guideline we review the best evidence supporting these commonly used strategies for high-grade dysplasia to better define management and guide future investigation.
巴雷特食管伴高级别异型增生的管理存在争议。传统的治疗标准是食管切除术。然而,许多中心越来越多地采用一些旨在保留食管的治疗选择。这些保留食管的方法包括内镜监测、黏膜消融和内镜黏膜切除术。在本指南中,我们回顾了支持这些常用于高级别异型增生的策略的最佳证据,以更好地明确管理并指导未来的研究。