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可吸入化妆品滑石粉的正常使用水平:初步研究。

Normal use levels of respirable cosmetic talc: preliminary study.

机构信息

Inveresk Research International Limited, Edinburgh EH21 7UB, Scotland.

出版信息

Int J Cosmet Sci. 1979 Jun;1(3):177-86. doi: 10.1111/j.1467-2494.1979.tb00212.x.

Abstract

Synopsis This preliminary study was undertaken to provide data from which a more comprehensive investigation to establish the safety in-use of cosmetic talcs could be designed. Methods for collecting and analysing respirable talc generated during the use of loose face powder and adult and baby dusting powders were established. Respirable particles in the air were separated from larger size particles by means of a cyclone and were collected on membrane filters. The collected dust was dissolved in acid and the solution was analysed for magnesium by atomic absorption spectroscopy. From the results the concentrations of talc in the air samples were calculated. The method was used to monitor the in-use levels of a range of cosmetic talcs. Mean concentrations in air sampled for 5 min from the start of use of Chinese grades and Italian 00000 grades of talc formulated for use as loose face powder, adult dusting powder and baby dusting powder were 0.48, 1.13 and 0.21 mg m(-3), respectively. Higher levels were found with micronised adult dusting powder (mean concentration 1.9 mg m(-3)). There was no evidence that the presence of perfume in the talc or the ambient relative humidity in the range 54-74% during use affected the levels of respirable talc, but high relative humidity <90% reduced the amount of respirable talc.

摘要

概要 本初步研究旨在提供数据,以便能够设计出更全面的调查,以确定化妆品滑石粉在使用中的安全性。 建立了收集和分析使用松散面部粉以及成人和婴儿爽身粉时产生的可吸入滑石粉的方法。 通过旋风将空气中的可吸入颗粒与较大粒径的颗粒分离,并将其收集在膜过滤器上。 将收集到的灰尘溶解在酸中,并通过原子吸收光谱法分析溶液中的镁。 根据结果计算出空气中滑石粉的浓度。 该方法用于监测一系列化妆品滑石粉的使用水平。 从使用开始 5 分钟内,从中国等级和意大利 00000 等级的滑石粉中采样,这些滑石粉被配方用于松散面部粉、成人爽身粉和婴儿爽身粉,空气中的平均浓度分别为 0.48、1.13 和 0.21 mg/m³。 与微米化成人爽身粉(平均浓度 1.9 mg/m³)相比,发现浓度更高。 没有证据表明滑石粉中香料的存在或使用过程中 54-74%的环境相对湿度会影响可吸入滑石粉的水平,但相对湿度>90%会减少可吸入滑石粉的量。

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