Rau H
Eberhard-Karls University of Tübingen, Clinical and Physiological Psychology Division, Germany.
Psychophysiology. 1991 Mar;28(2):231-9. doi: 10.1111/j.1469-8986.1991.tb00415.x.
This paper presents evidence that phasic changes in T-wave amplitude vary as a function of task conditions and beta-adrenergic drugs. Three experiments were designed to test the sensitivity of T-wave amplitude to manipulations in sympathetic arousal. In the first experiment, T-wave amplitude was recorded during an active behavioral task in which 32 subjects believed that they could control the duration of an aversive white noise and during a passive behavioral task in which another 30 subjects knew that they had no control. T-wave amplitude decreased to a greater extent in the active behavior group than in the passive group. In the second experiment, 9 subjects receiving one of two beta-adrenergic blockers and 10 subjects receiving placebo completed the active task. Task-induced reductions in T-wave amplitude were systematically blocked by the beta blockers. In the third experiment, 5 subjects received placebos and 15 received one of two different beta blockers. All subjects performed a mental arithmetic task. Subjects receiving a placebo, but not those receiving beta blockade, exhibited a significant reduction in T-wave amplitude during mental arithmetic.
本文提供的证据表明，T波振幅的相位变化随任务条件和β-肾上腺素能药物而变化。设计了三个实验来测试T波振幅对交感神经兴奋操作的敏感性。在第一个实验中，在一项主动行为任务中记录T波振幅，其中32名受试者认为他们可以控制厌恶白噪声的持续时间，在另一项被动行为任务中，另外30名受试者知道他们无法控制。主动行为组的T波振幅下降幅度大于被动组。在第二个实验中，9名接受两种β-肾上腺素能阻滞剂之一的受试者和10名接受安慰剂的受试者完成了主动任务。β受体阻滞剂系统性地阻断了任务诱导的T波振幅降低。在第三个实验中，5名受试者接受安慰剂，15名受试者接受两种不同β受体阻滞剂之一。所有受试者都进行了心算任务。接受安慰剂的受试者在心算过程中T波振幅显著降低，而接受β受体阻滞剂的受试者则没有。
