Chibisov S M, Rapoport S I, Katinas G S
Klin Med (Mosk). 2009;87(3):68-70.
Patient N presented with a well-apparent abnormality of chronological structure of heart beat biorhythms despite the absence of subjective complaints throughout the six-month long observation period. It was shown that AP peaks were associated with a significant decrease of circadian index (CI), i.e. the development of a rigid daily heart contraction rhythm. The reduction of CI as a specific indicator of stability of the daily cardiac contraction rhythm gave evidence of altered vegetative regulation of cardiac function during hypertension. Rigidity of the daily heart contraction rhythm increased with increasing severity of the disease. Smoothing of the circadian rhythm profile suggests depletion of adaptive reserve and the development of the "denervated" heart phenomenon. Cardioversion created a tendency towards normalization of circadian index.
患者N在长达六个月的观察期内,尽管没有主观不适,但心跳生物节律的时间结构存在明显异常。结果显示,动作电位峰值与昼夜节律指数(CI)显著降低相关,即出现了严格的每日心脏收缩节律。CI作为每日心脏收缩节律稳定性的特定指标降低,表明高血压期间心脏功能的自主调节发生了改变。每日心脏收缩节律的严格程度随疾病严重程度的增加而增加。昼夜节律曲线的平滑表明适应性储备耗竭和“去神经”心脏现象的出现。心脏复律使昼夜节律指数有趋于正常化的趋势。