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α粒子放射生物学。II. 使用平行板电离室和表面势垒探测器对低能α粒子进行剂量测定

Radiobiology of alpha particles. II. Dosimetry of low-energy alpha particles using parallel-plate ionization chambers and a surface barrier detector.

作者信息

Eisen Y, Harvey W F, Raju M R

机构信息

Dose Assessment Section, Los Alamos National Laboratory, New Mexico 87545.

出版信息

Radiat Res. 1991 Nov;128(2):197-203.

PMID:1947016
Abstract

Three small parallel-plate ionization chambers were developed for measuring dose rates, of primarily low-energy alpha particles in the energy range 0.4-3.5 MeV, at a defined cell-Mylar interface. Spectral energy distributions of these alpha particles were also measured at the same position using a specially designed small-area silicon surface barrier detector. Dose rates were derived from the spectral distributions and compared with those derived from the ionization chambers. Different alpha-particle energies were obtained using a 144-MBq 238Pu collimated source and a variety of Mylar moderator foils of different thicknesses. These measurements, extended to mean alpha-particle energies as low as 0.4 MeV, will enable us to correlate radiobiological data with effects of alpha particles terminating in different regions of cell nuclei.

摘要

开发了三个小型平行板电离室,用于在特定的细胞-聚酯薄膜界面处测量主要为能量范围在0.4-3.5 MeV的低能α粒子的剂量率。还使用专门设计的小面积硅表面势垒探测器在同一位置测量了这些α粒子的能谱能量分布。剂量率从能谱分布中得出,并与从电离室得出的剂量率进行比较。使用144 MBq的238Pu准直源和各种不同厚度的聚酯薄膜慢化箔获得了不同的α粒子能量。这些测量扩展到平均α粒子能量低至0.4 MeV,将使我们能够将放射生物学数据与终止于细胞核不同区域的α粒子的效应相关联。

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