Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
J Gynecol Oncol. 2008 Dec;19(4):218-22. doi: 10.3802/jgo.2008.19.4.218. Epub 2008 Dec 29.
The Gynecologic Oncology Group (GOG) has conducted multiple trials related to malignancies of the uterine corpus. Recently, several of these trials have been presented and/or published. Areas of focus included the feasibility of laparoscopic staging for endometrial cancer, the adjuvant management of locally advanced endometrial cancer, whole abdominal irradiation in maximally resected advanced endometrial carcinoma, and combination chemotherapy regimens for stage I and II carcinosarcoma after primary surgery and for advanced or recurrent carcinosarcoma. This article will discuss the background and details of each of these important advances.
妇科肿瘤学组(GOG)已经开展了多项与子宫体恶性肿瘤相关的临床试验。最近,其中的几项试验已经公布。重点领域包括腹腔镜分期子宫内膜癌的可行性、局部晚期子宫内膜癌的辅助治疗、最大限度切除晚期子宫内膜癌的全腹部放疗,以及Ⅰ期和Ⅱ期癌肉瘤患者手术后和晚期或复发性癌肉瘤患者的联合化疗方案。本文将讨论这些重要进展的背景和细节。