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[通过直接淋巴细胞免疫细胞毒性检测劳氏病毒转化细胞中的抗原]

[Detection, by direct lymphocyte immunocytotoxicity, of antigens in cells transformed by Rous virus].

作者信息

Dambrine G, Cauchy L

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Apr 18;284(15):1477-9.

PMID:194724
Abstract

The hamster cells transformed by the Rous Sarcoma Virus (V.S.R.) evidenced surface antigenic alterations that were detected by a method of cellular mediated immunocytotoxicity. Immune hamster lymphocytes were added to tritiated proline prelabeled target cells. These lymphocytes were able to lyse specifically the V.S.R. transformed cells.

摘要

被劳氏肉瘤病毒（V.S.R.）转化的仓鼠细胞表现出表面抗原性改变，这是通过细胞介导的免疫细胞毒性方法检测到的。将免疫仓鼠淋巴细胞添加到用氚标记的脯氨酸预先标记的靶细胞中。这些淋巴细胞能够特异性地裂解被V.S.R.转化的细胞。

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