Milloy M-J S, Buxton Jane, Wood Evan, Li Kathy, Montaner Julio S G, Kerr Thomas
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada.
BMC Public Health. 2009 May 27;9:156. doi: 10.1186/1471-2458-9-156.
While incarceration has consistently been associated with a higher risk of HIV infection for individuals who use injection drugs (IDU), the effect of incarceration on the post-release risk environment remains poorly described. We sought to assess the impact of incarceration on risk factors for HIV infection after release from prison in a sample of active IDU in Vancouver, Canada.
Using a prospective cohort of community-recruited IDU followed from May 1, 1996 to November 30, 2005, we examined contingency tables and performed linear growth curve analyses to assess changes in the prevalence of independent risk factors for HIV infection from before to after a period of incarceration among participants reporting incarceration and a matched control group.
Of the 1603 participants followed-up over the study period, 147 (9.2%) were eligible for an analysis of post-incarceration risk behaviours and 742 (46.3%) were used as matched controls. Significant differences were found in one or both groups for the prevalence of frequent cocaine injection, requiring help injecting, binge drug use, residence in the HIV outbreak epicentre, sex-trade participation and syringe sharing (all p < 0.05) after incarceration. In linear growth curve adjusted for age, gender and ethnicity, syringe sharing was significantly more common in those recently released from prison (p = 0.03) than in the control group.
In a sample of Canadian IDU, we did not observe any effect of incarceration on the prevalence of several behaviours that are risk factors for HIV infection, including intensity of drug use or participation in the sex trade. However, those recently released from prison were more likely to report syringe sharing that those in a matched control group.
虽然监禁一直与注射吸毒者(IDU)感染艾滋病毒的较高风险相关,但监禁对释放后风险环境的影响仍鲜有描述。我们试图评估监禁对加拿大温哥华一组活跃的注射吸毒者出狱后艾滋病毒感染风险因素的影响。
利用一个前瞻性队列,该队列是从1996年5月1日至2005年11月30日招募的社区注射吸毒者,我们检查了列联表并进行了线性增长曲线分析,以评估报告有监禁经历的参与者及其匹配对照组在监禁前后艾滋病毒感染独立风险因素流行率的变化。
在研究期间随访的1603名参与者中,147人(9.2%)符合监禁后风险行为分析的条件,742人(46.3%)用作匹配对照组。监禁后,两组中频繁注射可卡因、需要他人协助注射、狂饮吸毒、居住在艾滋病毒爆发中心地区、参与性交易和共用注射器的流行率存在一项或两项显著差异(所有p<0.05)。在根据年龄、性别和种族进行调整的线性增长曲线分析中,刚出狱者共用注射器的情况显著多于对照组(p = 0.03)。
在一组加拿大注射吸毒者样本中,我们未观察到监禁对几种艾滋病毒感染风险行为的流行率有任何影响,包括吸毒强度或参与性交易。然而,刚出狱者比匹配对照组更有可能报告共用注射器的情况。