Imbelloni Luiz Eduardo, Beato Lúcia, Gouveia M A
Clínica São Bernardo, Casa de Saúde Santa Maria, Rio de Janeiro.
Rev Bras Anestesiol. 2002 Sep;52(5):542-8. doi: 10.1590/s0034-70942002000500004.
Restricted sympathetic block during spinal anesthesia may minimize hemodynamic changes. In theory, the use of non-isobaric local anesthetics may induce unilateral anesthesia and limit sympathetic blockade to one side of the body. The local anesthetic dose and the time patients need to remain in the lateral position for achieving unilateral spinal anesthesia are not known. This prospective study investigated the incidence of unilateral spinal anesthesia following injection through a 27G Quincke needle of 0.15% hypobaric bupivacaine, prepared with 1.5 ml standard isobaric bupivacaine plus fentanyl (25 microg), in patients in the lateral position with the limb to be operated upwards.
Spinal anesthesia with 0.15% bupivacaine + fentanyl (25 microg) was induced through a 27G Quincke needle in 22 ASA I and II patients undergoing orthopedic surgery. Dural puncture was performed with the patient in the lateral position with the side to be operated upwards. After removal of 3 to 5 ml of CSF, 5 ml of the hypobaric bupivacaine-fentanyl mixture were injected at a speed of 1 ml.15 s-1. Sensory and motor block (pinprick/scale 0 to 3) were compared between operated and contralateral sides.
Motor and sensory blocks in operated and contralateral sides were significantly different in all moments for both groups. Unilateral spinal anesthesia was obtained in 71% of the patients. No hemodynamic changes were observed in any patient. No patient developed post-dural puncture headache.
Hypobaric 0.15% bupivacaine (7.5 mg) associated to fentanyl provided a predominantly unilateral block after twenty minutes in the lateral position. Major advantages of unilateral spinal anesthesia were hemodynamic stability, patient satisfaction and the absence of post-dural puncture headache.
脊髓麻醉期间限制交感神经阻滞可使血流动力学变化降至最低。理论上,使用非等比重局麻药可能会诱导单侧麻醉,并将交感神经阻滞限制在身体的一侧。目前尚不清楚实现单侧脊髓麻醉所需的局麻药剂量以及患者需要保持侧卧位的时间。本前瞻性研究调查了在肢体向上的侧卧位患者中,通过27G Quincke针注射由1.5 ml标准等比重布比卡因加芬太尼(25微克)配制的0.15%轻比重布比卡因后单侧脊髓麻醉的发生率。
对22例接受骨科手术的美国麻醉医师协会(ASA)I级和II级患者,通过27G Quincke针诱导0.15%布比卡因+芬太尼(25微克)的脊髓麻醉。患者处于手术侧向上的侧卧位时进行硬膜穿刺。抽出3至5 ml脑脊液后,以1 ml·15 s⁻¹的速度注入5 ml轻比重布比卡因-芬太尼混合液。比较手术侧和对侧的感觉和运动阻滞(针刺痛觉/0至3级)。
两组在所有时间点手术侧和对侧的运动和感觉阻滞均有显著差异。71%的患者获得了单侧脊髓麻醉。所有患者均未观察到血流动力学变化。无患者发生硬膜穿刺后头痛。
0.15%轻比重布比卡因(7.5毫克)联合芬太尼在侧卧位20分钟后主要产生单侧阻滞。单侧脊髓麻醉的主要优点是血流动力学稳定、患者满意度高以及无硬膜穿刺后头痛。