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术前主动脉瓣关闭不全程度是否会影响保留瓣膜手术的早期和中期结果?

Does preoperative degree of aortic insufficiency influence early and midterm results of sparing surgery?

作者信息

Pacini Davide, Botta Luca, Bracchetti Giovanni, Massi Francesco, Di Marco Luca, Cattabriga Iolter, Di Bartolomeo Roberto

机构信息

Cardiothoracovascular Department, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.

出版信息

Acta Cardiol. 2009 Apr;64(2):171-6. doi: 10.2143/AC.64.2.2035340.

Abstract

OBJECTIVE

Aortic valve-sparing operations have shown excellent results in patients with aortic root and or ascending aorta aneurysm. Aortic valve regurgitation is frequently detected in these patients as a result of significant dilation of the aortic root.The aim of this study was to assess the impact of preoperative aortic incompetence degree on the early and midterm outcomes of sparing surgery.

METHODS

From September 2001 to July 2006, 84 patients with aortic root aneurysm underwent aortic valve-sparing surgery according to the reimplantation technique. Depending on preoperative grade of aortic insufficiency (AI), two groups were identified: 31 patients (study group, SG) with AI grade III-IV and 53 (control group, CG) with AI grade II or less. The Gelweave Valsalva prosthesis was used in 76 patients (90.5%). Intraoperative, perioperative variables and outcomes at follow-up were retrospectively compared between the groups.

RESULTS

Patient demographics and types of operations were comparable between groups. Early mortality rates were almost identical in both groups (3.2% SG vs. 5.7% CG; P = 0.961); at follow-up (FU), no patient died in both groups. Grade III-IV AI was similar in both groups early postoperatively (6.4% SG vs. 3.8% CG; P = 0.981) and during follow-up (13.3% vs. 8%; P = 0.755). Reoperaton rate for AI was 3.3% in SG vs. 6% in CG (P = 0.980).

CONCLUSIONS

Preoperative degree of aortic regurgitation does not impair the outcomes of the valve-sparing operation which seem to depend on more factors. Early results were affected by the learning curve but midterm outcomes showed a progressive improvement. Patients with satisfactory reconstruction show stable results over time.

摘要

目的

保留主动脉瓣手术在主动脉根部和/或升主动脉瘤患者中已显示出优异的效果。由于主动脉根部显著扩张,这些患者常出现主动脉瓣反流。本研究的目的是评估术前主动脉瓣关闭不全程度对保留主动脉瓣手术早期和中期结果的影响。

方法

2001年9月至2006年7月,84例主动脉根部瘤患者根据再植入技术接受了保留主动脉瓣手术。根据术前主动脉瓣关闭不全(AI)分级,分为两组:31例AI分级为III-IV级的患者(研究组,SG)和53例AI分级为II级或更低的患者(对照组,CG)。76例患者(90.5%)使用了Gelweave Valsalva人工瓣膜。回顾性比较两组患者术中、围手术期变量及随访结果。

结果

两组患者的人口统计学特征和手术类型具有可比性。两组早期死亡率几乎相同(SG为3.2%,CG为5.7%;P = 0.961);随访时,两组均无患者死亡。术后早期两组III-IV级AI相似(SG为6.4%,CG为3.8%;P = 0.981),随访期间也相似(分别为13.3%和8%;P = 0.755)。SG组AI再次手术率为3.3%,CG组为6%(P = 0.980)。

结论

术前主动脉瓣反流程度并不影响保留主动脉瓣手术的结果,手术结果似乎取决于更多因素。早期结果受学习曲线影响,但中期结果显示出逐步改善。重建满意的患者随时间推移结果稳定。

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