Dan Dilip, Seetahal Shiva, Persad Rajendra
Department of Surgery, University of the West Indies, Trinidad Campus, San Fernando General Hospital, San Fernando, Trinidad.
J Natl Med Assoc. 2009 May;101(5):462-5. doi: 10.1016/s0027-9684(15)30933-0.
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms that account for 0.2% of all GI neoplasms. We report a case of a 62-year-old male with a large esophageal GIST, and discuss the pathophysiology of the disease and the current management principles. This case is noteworthy because it documents a rare lesion in the esophagus that presents like other neoplastic diseases in this organ that usually carry a poor prognosis. An aggressive approach (e.g., more radical surgery, radiotherapy, and chemotherapy) might have been pondered based purely on the size of the lesion in this patient. It is important that primary care physicians and surgeons be aware of the possibility of the presence of this potentially curable lesion so as to avoid overtreatment.
胃肠道间质瘤（GISTs）是罕见的间叶性肿瘤，占所有胃肠道肿瘤的0.2%。我们报告一例62岁男性患有巨大食管GIST的病例，并讨论该疾病的病理生理学及当前的治疗原则。该病例值得关注，因为它记录了食管中一种罕见病变，其表现与该器官中其他通常预后不良的肿瘤性疾病相似。单纯基于该患者病变的大小，可能曾考虑采取积极的治疗方法（如更根治性的手术、放疗和化疗）。初级保健医生和外科医生必须意识到存在这种潜在可治愈病变的可能性，以避免过度治疗。
