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两家教学医院收治儿童的免疫性血小板减少性紫癜

Immune thrombocytopenic purpura among the children attending at two teaching hospitals.

作者信息

Hafiz Md Golam, Mannan M A, Amin Syed Khairul, Islam Afiqul, Rahman Fazlur

机构信息

Department of Pediatric Hematology and Oncology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladesh.

出版信息

Bangladesh Med Res Counc Bull. 2008 Dec;34(3):94-8.

Abstract

The presenting features, diagnostic evaluation, seasonal variation and management performed in 110 children with immune thrombocytopenic purpura (ITP) attending at two tertiary level hospitals were evaluated. A peak incidence of children with ITP was observed during the month of June, July and the first step was found in May and lowest in the month of October to December. Mean initial platelet count was 65.5 x 10(9)/L. 35 patients with ITP did not require any treatment who were kept under observation and the rest 75 children who were admitted to hospital given platelet count enhancing treatment- intravenous immunoglobulin in 9, corticosteroids in 60 or both in 6 children with ITP. Intracranial hemorrhages were noticed in two children with ITP. So, this study suggests that ITP had special predilection during summer season and the least in winter along with variable approaches to management of these children.

摘要

对两家三级医院收治的110例免疫性血小板减少性紫癜(ITP)患儿的临床表现、诊断评估、季节变化及治疗情况进行了评估。ITP患儿的发病高峰出现在6月、7月,首发症状出现在5月,10月至12月发病率最低。初始血小板平均计数为65.5×10⁹/L。35例ITP患儿未接受任何治疗,仅接受观察,其余75例住院患儿接受了提高血小板计数的治疗——9例患儿接受静脉注射免疫球蛋白,60例患儿接受皮质类固醇治疗,6例患儿同时接受了这两种治疗。2例ITP患儿出现颅内出血。因此,本研究表明,ITP在夏季有特殊偏好,冬季最少,且对这些患儿的治疗方法多样。

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