Roberts J, Baskin S I, Goldberg P B
Exp Aging Res. 1977 Jan;3(1):75-84. doi: 10.1080/03610737708257089.
Data relating to the effects of aging on the neuromuscular system of rats have been reviewed and summarized. Age effects of muscle, nerve and neuromuscular junction are presented only in a descriptive, qualitative manner, primarily due to paucity of well controlled experimentation in this area. Certain morphological and biochemical changes taking place with aging of the neuromuscular system are discussed, but no conclusive hypotheses can be presented at this time explaining diminution of motor activity in old animals.
有关衰老对大鼠神经肌肉系统影响的数据已得到综述和总结。肌肉、神经和神经肌肉接头的衰老效应仅以描述性、定性的方式呈现,主要是因为该领域缺乏严格控制的实验。文中讨论了神经肌肉系统衰老过程中发生的某些形态学和生化变化,但目前无法提出确凿的假说来解释老年动物运动活性降低的原因。