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胃腺癌罕见的骨骼肌转移

Unusual skeletal muscle metastasis from gastric adenocarcinoma.

作者信息

Tougeron D, Hamidou H, Dujardin F, Maillard C, Di Fiore F, Michel P

机构信息

Digestive Oncology Unit, Department of Gastroenterology, Rouen University Hospital, Northwest Cancéropôle, Rouen, France.

出版信息

Gastroenterol Clin Biol. 2009 Jun-Jul;33(6-7):485-7. doi: 10.1016/j.gcb.2009.03.018. Epub 2009 May 27.

Abstract

Patients with gastric adenocarcinoma frequently develop hepatic metastases or peritoneal carcinosis but involvement of the skeletal muscle is extremely rare. We report the case of a 71-year-old man with a painful soft tissue mass in the right shoulder. Two years previously, the patient had been treated for a locally advanced gastric carcinoma (surgery plus chemoradiotherapy). Surgical exploration with biopsy showed skeletal muscle metastasis from the gastric adenocarcinoma in the deltoid muscle. Chemoradiotherapy resulted in complete regression of symptoms from the metastatic lesion. The patient is alive and free of recurrence in the deltoid muscle after a follow-up of 13 months. Based on this case study, the difficulty of diagnosing skeletal muscle metastases, the prognosis and treatment options are discussed.

摘要

胃腺癌患者常发生肝转移或腹膜癌,但骨骼肌受累极为罕见。我们报告一例71岁男性,其右肩部有一疼痛性软组织肿块。两年前,该患者曾接受局部晚期胃癌治疗(手术加放化疗)。手术探查及活检显示三角肌存在胃腺癌的骨骼肌转移。放化疗使转移病灶症状完全消退。随访13个月后,患者存活,三角肌未复发。基于此病例研究,讨论了骨骼肌转移的诊断难点、预后及治疗选择。

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