Pull ter Gunne Albert F, Cohen David B
Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Spine (Phila Pa 1976). 2009 Jun 1;34(13):1422-8. doi: 10.1097/BRS.0b013e3181a03013.
A retrospective cohort study to identify rates and analyze the risk factors for postoperative spinal wound infection.
To determine significant risk factors for postoperative spinal wound infection by comparing those patients who developed a postoperative wound infection with the rest of the cohort.
A surgical site infection (SSI) is a common complication after spinal surgery. SSI leads to higher morbidity, mortality, and healthcare costs. To develop strategies to reduce the risk for SSI, independent risk factors for SSI should be identified.
The electronic patient record of all 3174 patients who underwent orthopedic spinal surgery at out institution were abstracted. Individual patient and perioperative characteristics were stored in an electronic database.
In total, 132 (4.2%) patients were found to have an SSI with 84 having deep based infection. Estimated blood loss over 1 liter (P = 0.017), previous SSI (P = 0.012) and diabetes (P = 0.050) were found to be independent statistically significant risk factors for SSI. Obesity (P = 0.009) was found to significantly increase the risk of superficial infection, whereas anterior spinal approach decreased the risk (P = 0.010). Diabetes (P = 0.033), obesity (P = 0.047), previous SSI (P = 0.009), and longer surgeries (2-5 hours [P = 0.023] and 5 or more hours [P = 0.009]) were found to be independent significant risk factors for deep SSI.
SSI is commonly seen after spinal surgery. In our study, we identified independent risk factors for both deep and superficial SSI. Identification of these risk factors should allow us to design protocols to decrease the risk of SSE in future patients.
一项回顾性队列研究,以确定术后脊柱伤口感染的发生率并分析其危险因素。
通过比较发生术后伤口感染的患者与队列中的其他患者,确定术后脊柱伤口感染的显著危险因素。
手术部位感染(SSI)是脊柱手术后的常见并发症。SSI会导致更高的发病率、死亡率和医疗费用。为制定降低SSI风险的策略,应确定SSI的独立危险因素。
提取了在我们机构接受骨科脊柱手术的所有3174例患者的电子病历。个体患者和围手术期特征存储在电子数据库中。
总共发现132例(4.2%)患者发生SSI,其中84例为深部感染。估计失血量超过1升(P = 0.017)、既往SSI(P = 0.012)和糖尿病(P = 0.050)被发现是SSI的独立统计学显著危险因素。肥胖(P = 0.009)被发现显著增加浅表感染的风险,而前路脊柱手术则降低了风险(P = 0.010)。糖尿病(P = 0.033)、肥胖(P = 0.047)、既往SSI(P = 0.009)以及手术时间较长(2 - 5小时[P = 0.023]和5小时或更长时间[P = 0.009])被发现是深部SSI的独立显著危险因素。
SSI在脊柱手术后很常见。在我们的研究中,我们确定了深部和浅表SSI的独立危险因素。识别这些危险因素应使我们能够设计方案以降低未来患者发生手术部位感染的风险。