人乳头瘤病毒分子概况与致癌机制：综述

Human papilloma virus molecular profile and mechanisms of cancerogenesis: a review.

作者信息

Deligeoroglou E, Christopoulos P, Aravantinos L, Papadias K

机构信息

Division of Pediatric-Adolescent Gynecology and Reconstructive Surgery, 2nd Department of Obstetrics and Gynecology, Medical School, University of Athens, Aretaieion Hospital, Athens, Greece.

出版信息

Eur J Gynaecol Oncol. 2009;30(2):128-32.

PMID:19480239

Abstract

Human papilloma virus (HPV) is frequently present in the genital tract. It causes various lesions at the mucosa of both sexes. It is considered as a causative factor of cervical cancer even if all women infected by HPV will not develop the disease. This article reviews aspects of HPV molecular biology and the mechanisms of cancerogenesis in HPV infected females.

摘要

人乳头瘤病毒（HPV）常存在于生殖道。它会导致两性黏膜出现各种病变。即使所有感染HPV的女性并非都会患上宫颈癌，但HPV仍被视为宫颈癌的致病因素。本文综述了HPV分子生物学的相关方面以及HPV感染女性的致癌机制。