粒细胞与巨噬细胞的调控：分子、细胞及临床层面
Control of granulocytes and macrophages: molecular, cellular, and clinical aspects.
作者信息
Metcalf D
机构信息
Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia.
出版信息
Science. 1991 Oct 25;254(5031):529-33. doi: 10.1126/science.1948028.
PMID:1948028
Abstract
The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.
摘要
两种重要的白细胞，即粒细胞和巨噬细胞的生成及功能活性主要受一组糖蛋白集落刺激因子的调节。集落刺激因子已通过重组技术大量生产，目前已证明在预防或抑制各种血细胞生成低于正常水平或有缺陷的个体发生感染方面具有价值。
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