恶性黑色素瘤的皮肤转移——能有多难？

Cutaneous metastases of malignant melanoma--how difficult can it be?

作者信息

Zurac Sabina, Andrei R, Petsakos G, Nichita Luciana, Bastian Alexandra, Micu Gianina, Gramadă Eliza, Popp Cristiana, Stăniceanu Florica, Petrescu Stefana, Negroiu Gabriela, Giurcăneanu Dorina, Chiţu Virginia

机构信息

Department of Pathology, Colentina University Hospital, Romania.

出版信息

Rom J Intern Med. 2008;46(4):375-8.

PMID:19480306

Abstract

Malignant melanoma is one of the most aggressive skin neoplasms with histopathological-based therapeutic approach. Unfortunately, in some cases, even the elementary issue of dealing with a primary or metastatic lesion may be sometimes incredible difficult to settle. We studied 11 cases of malignant melanomas that required careful histopathological and immunohistochemical analysis to differentiate between primary and secondary tumor. We evaluated epidermotropism of primary MM including synchronous tumors, local recurrences and metastases.

摘要

恶性黑色素瘤是最具侵袭性的皮肤肿瘤之一，采用基于组织病理学的治疗方法。不幸的是，在某些情况下，即使是处理原发性或转移性病变这样的基本问题，有时也可能极难解决。我们研究了11例恶性黑色素瘤病例，这些病例需要仔细的组织病理学和免疫组化分析以区分原发性和继发性肿瘤。我们评估了原发性黑色素瘤的亲表皮性，包括同时性肿瘤、局部复发和转移。