Su Shan-Yu, Wei Ching-Chuan, Hsieh Ching-Liang, Tsao Jung-Ying, Li Tsai-Chung, Lin Tsai-Hui, Chang Hen-Hong, Lo Lun-Chien
Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan.
J Altern Complement Med. 2009 Jun;15(6):645-52. doi: 10.1089/acm.2008.0022.
The aim of this study was to investigate the effects of the menstrual cycle on the pulse pressure waveforms in women with regular biphasic cycles.
We recruited 36 biphasic healthy eumenorrheic volunteers. Pulse pressure waveforms from the radial artery were recorded by sphygmography in both hands, each with three measurement positions and three different preload pressures, in a total of 18 measured points. The experimental design was single blinded and the technician who measured the waveforms did not know the menstrual time point of the subjects. The parameters included the pulse rate (PR), the height of the main wave (h(1)), the height of the dicrotic wave (h(3)), the rapid ejection time, the single systolic area (sSA), and the 1-minute systolic area (tSA).
Our results showed that PR was significantly greater during the luteal phase (81.5 +/- 1.5/minutes versus 78.3 +/- 1.5/minutes, p < 0.05) with an accompanying greater h(1), h(3), sSA, and tSA (p < 0.05). We also demonstrated that h(1), h(3), sSA, and tSA increased with preload pressures and decreased when the detector was moved proximally, possibly a resultant of differences in the diameter and depth of radial artery. Furthermore, we found that h(3) taken from the right hand was larger than that taken from the left hand and may reflect a shorter and simpler route of the right radial artery.
We conclude that pulse waveforms taken from the radial artery may assist in the identification of greater plasma volume, ventricular ejection volume, and vasodilatation increase in the luteal compared to the follicular phase.
本研究旨在调查月经周期对月经周期规律呈双相型的女性脉压波形的影响。
我们招募了36名月经周期呈双相型的健康有排卵性志愿者。通过脉搏描记法记录双手桡动脉的脉压波形，每只手有三个测量位置和三种不同的预负荷压力，总共18个测量点。实验设计为单盲，测量波形的技术人员不知道受试者的月经时间点。参数包括脉搏率（PR）、主波高度（h(1)）、重搏波高度（h(3)）、快速射血时间、单收缩期面积（sSA）和1分钟收缩期面积（tSA）。
我们的结果显示，黄体期的PR显著更高（81.5±1.5/分钟对78.3±1.5/分钟，p<0.05），同时h(1)、h(3)、sSA和tSA也更大（p<0.05）。我们还证明，h(1)、h(3)、sSA和tSA随预负荷压力增加而增加，当探测器向近端移动时则降低，这可能是桡动脉直径和深度差异的结果。此外，我们发现从右手测得的h(3)大于从左手测得的h(3)，这可能反映了右桡动脉路径更短更简单。
我们得出结论，与卵泡期相比，从桡动脉获取的脉搏波形可能有助于识别黄体期更大的血浆量、心室射血量和血管舒张增加情况。
