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文献综述:对于老年前列腺癌患者,静观等待是一种可行的治疗选择吗?

Critical review: is watchful waiting a viable management option for older men with prostate cancer?

机构信息

Duke University School of Nursing, Durham, North Carolina 27710, USA.

出版信息

Am J Mens Health. 2007 Mar;1(1):18-28. doi: 10.1177/1557988306294161.

Abstract

Prostate cancer is the most commonly diagnosed cancer and the second-leading cause of death from cancer in U.S. men. For older men with early-stage prostate cancer, watchful waiting (also referred to as surveillance, expectant management, deferred/delayed therapy, or active monitoring) is a reasonable approach to aggressive therapy. The purpose of this article is to critically review published studies on the watchful waiting management option for prostate cancer within the past 5 years. The review of documented reports on watchful waiting reveals that there are both negative and positive indications toward watchful waiting. Further research is needed to change the perception of watchful waiting as a "do nothing" approach to the management of prostate cancer or a "death sentence" and to develop interventions that assist men to manage the uncertainty associated with living with prostate cancer to improve health and advance quality of life.

摘要

前列腺癌是美国男性最常见的癌症,也是癌症死亡的第二大原因。对于患有早期前列腺癌的老年男性,观察等待(也称为监测、期待治疗、延迟/推迟治疗或主动监测)是一种合理的积极治疗方法。本文旨在批判性地回顾过去 5 年内关于前列腺癌观察等待管理选择的已发表研究。对观察等待的记录报告的回顾表明,观察等待既有负面的也有积极的指征。需要进一步的研究来改变观察等待作为前列腺癌管理的“不作为”方法或“死刑”的看法,并开发干预措施,帮助男性应对与前列腺癌共存相关的不确定性,以改善健康并提高生活质量。

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