Skaguchi Toshifumi, Shigematsu Takashi
Division of Nephrology and Blood Purification, Wakayama Medical University.
Clin Calcium. 2009 Jun;19(6):844-51.
In spite of various cause of hyperphosphatemia, there is a limited number of modality which include restriction of phosphate intake, phosphate binder, extra cellular fluid expansion and blood purification. Each therapy has certain deficit but combination of those may get preferable consequence. Now various new phosphate binders and the inhibitors of sodium-dependent phosphate transporters are being developed. Those agents might promise a better outcome of the treatment of hyperphosphatemia.
尽管高磷血症有多种病因，但治疗方法有限，包括限制磷摄入、使用磷结合剂、细胞外液扩容和血液净化。每种治疗方法都有一定的不足，但联合使用可能会取得更好的效果。目前正在研发各种新型磷结合剂和钠依赖性磷转运体抑制剂。这些药物可能会为高磷血症的治疗带来更好的结果。
