• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一例严重的生殖器放射性坏死病例。

A dramatic case of genital radionecrosis.

机构信息

Hospital General de Zona 1 IMSS, Colima, Col. Universidad de Colima, Zaragoza 377 centro Colima, 28000, Colima, Mexico.

出版信息

Int Urol Nephrol. 2010 Mar;42(1):65-8. doi: 10.1007/s11255-009-9591-4. Epub 2009 May 31.

DOI:10.1007/s11255-009-9591-4
PMID:19484502
Abstract

BACKGROUND

Epidermoid carcinoma of the penis presents in 1% of malignant tumors in men. Penis cancer treatment has traditionally been total or partial amputation. There are authors who consider radiation to be part of penis cancer treatment in select cases--especially the use of brachytherapy and external radiation.

CLINICAL CASE

The case of a 48-year-old male who in 2004 presented with an ulcerated lesion of the penis that was left unattended to is presented. Two years later, he sought medical attention and physical examination revealed an ulcerated penile lesion with poorly defined edges and limited to the glans.

DIAGNOSIS

The lesion was biopsied and the histopathological study reported Epidermoid Carcinoma. After radiological studies, it was classified as stage T2-N0-M0.

TREATMENT

Total penectomy without lymphadenectomy was performed. The patient received adjuvant treatment of 15 sessions of cobalt radiation treatment at a dose of 3,500 cGy. Six months later, the patient noticed the presence of erythema at the genital and inguinal level which later ulcerated and extended toward the perineum. The disease progressed tragically and the patient died 2 years later.

摘要

背景

阴茎表皮样癌占男性恶性肿瘤的 1%。阴茎癌的传统治疗方法为全切除或部分切除。有作者认为,在某些情况下,包括近距离放射治疗和外照射在内的放射治疗可作为阴茎癌的治疗方法之一。

临床病例

报告了一名 48 岁男性的病例,他于 2004 年出现阴茎溃疡性病变,未予治疗。两年后,他寻求医疗救治,体格检查显示阴茎有溃疡性病变,边缘不清,局限于龟头。

诊断

对病变进行了活检,组织病理学研究报告为表皮样癌。经过影像学研究,该患者被归类为 T2N0M0 期。

治疗

行全阴茎切除术,未行淋巴结清扫术。患者接受了 15 次钴 60 放疗,剂量为 3500cGy。6 个月后,患者发现生殖器和腹股沟部位出现红斑,随后溃疡并向会阴部位延伸。病情恶化,患者在 2 年后死亡。

相似文献

1
A dramatic case of genital radionecrosis.一例严重的生殖器放射性坏死病例。
Int Urol Nephrol. 2010 Mar;42(1):65-8. doi: 10.1007/s11255-009-9591-4. Epub 2009 May 31.
2
A case of genital radionecrosis: the forgotten complication.一例生殖器放射性坏死:被遗忘的并发症。
Tunis Med. 2014 Jun;92(6):419-20.
3
Penile brachytherapy: results for 49 patients.阴茎近距离放射疗法:49例患者的治疗结果。
Int J Radiat Oncol Biol Phys. 2005 Jun 1;62(2):460-7. doi: 10.1016/j.ijrobp.2004.10.016.
4
High-dose-rate interstitial brachytherapy for the treatment of penile carcinoma.高剂量率组织间近距离放射疗法治疗阴茎癌
Strahlenther Onkol. 2004 Feb;180(2):123-5. doi: 10.1007/s00066-004-1124-6.
5
Treatment results and prognostic factors in 101 men treated for squamous carcinoma of the penis.101例阴茎鳞状细胞癌男性患者的治疗结果及预后因素
Int J Radiat Oncol Biol Phys. 1997 Jul 1;38(4):713-22. doi: 10.1016/s0360-3016(97)00068-0.
6
Penile brachytherapy-Retrospective review of a single institution.阴茎近距离放射治疗——单机构回顾性研究
Brachytherapy. 2015 Jul-Aug;14(4):525-30. doi: 10.1016/j.brachy.2015.01.005. Epub 2015 Apr 8.
7
Principles and practice of high-dose rate penile brachytherapy: Planning and delivery techniques.高剂量率阴茎近距离放射治疗的原则与实践:计划与实施技术。
Pract Radiat Oncol. 2018 Nov-Dec;8(6):e386-e391. doi: 10.1016/j.prro.2018.06.002. Epub 2018 Jun 8.
8
The efficacy of hyperbaric oxygen therapy in the treatment of medically refractory soft tissue necrosis after penile brachytherapy.高压氧疗法治疗阴茎近距离放射治疗后药物难治性软组织坏死的疗效
Brachytherapy. 2011 Nov-Dec;10(6):491-7. doi: 10.1016/j.brachy.2011.01.009. Epub 2011 Feb 23.
9
Low-dose brachytherapy for early stage penile cancer: a 20-year single-institution study (73 patients).早期阴茎癌的低剂量近距离放射治疗:一项为期20年的单机构研究(73例患者)。
Radiat Oncol. 2016 Jul 27;11:96. doi: 10.1186/s13014-016-0676-9.
10
The role of radiation therapy after incomplete resection of penile cancer.阴茎癌不完全切除术后放射治疗的作用。
Strahlenther Onkol. 2008 Jul;184(7):359-63. doi: 10.1007/s00066-008-1818-2. Epub 2008 Oct 1.

本文引用的文献

1
Advanced penile carcinoma.晚期阴茎癌
J Urol. 2003 Aug;170(2 Pt 1):359-65. doi: 10.1097/01.ju.0000062829.43654.5e.
2
Treatment results and prognostic factors in 101 men treated for squamous carcinoma of the penis.101例阴茎鳞状细胞癌男性患者的治疗结果及预后因素
Int J Radiat Oncol Biol Phys. 1997 Jul 1;38(4):713-22. doi: 10.1016/s0360-3016(97)00068-0.
3
Prophylactic lymphadenectomy vs observation vs inguinal biopsy in node-negative patients with invasive carcinoma of the penis.阴茎浸润性癌淋巴结阴性患者中预防性淋巴结清扫术与观察等待及腹股沟活检的比较
Jpn J Clin Oncol. 1993 Feb;23(1):53-8.
4
The results of primary radiation therapy in the management of squamous cell carcinoma of the penis.
Int J Radiat Oncol Biol Phys. 1993 Mar 15;25(4):623-8. doi: 10.1016/0360-3016(93)90008-j.
5
Squamous cell carcinoma of the penis. III. Treatment of regional lymph nodes.阴茎鳞状细胞癌。III. 区域淋巴结的治疗
J Urol. 1993 Mar;149(3):492-7. doi: 10.1016/s0022-5347(17)36126-8.
6
Correlation between the extent of nodal involvement and survival following groin dissection for carcinoma of the penis.阴茎癌腹股沟淋巴结清扫术后淋巴结受累范围与生存率的相关性。
Br J Urol. 1993 Nov;72(5 Pt 2):817-9. doi: 10.1111/j.1464-410x.1993.tb16273.x.
7
Role of radiation therapy in the treatment of carcinoma of the penis.放射治疗在阴茎癌治疗中的作用。
Br J Urol. 1994 Nov;74(5):646-51. doi: 10.1111/j.1464-410x.1994.tb09199.x.
8
Surgical treatment of invasive squamous cell carcinoma of the penis: retrospective analysis of 350 cases.阴茎浸润性鳞状细胞癌的外科治疗:350例回顾性分析
J Urol. 1994 May;151(5):1244-9. doi: 10.1016/s0022-5347(17)35222-9.
9
Interstitial brachytherapy for penile carcinoma: a multicentric survey (259 patients).
Radiother Oncol. 1995 Aug;36(2):83-93. doi: 10.1016/0167-8140(95)01574-z.
10
Histopathological study of radionecrosis in laryngeal carcinoma.
Laryngoscope. 1982 Feb;92(2):173-80. doi: 10.1002/lary.1982.92.2.173.