Hospital General de Zona 1 IMSS, Colima, Col. Universidad de Colima, Zaragoza 377 centro Colima, 28000, Colima, Mexico.
Int Urol Nephrol. 2010 Mar;42(1):65-8. doi: 10.1007/s11255-009-9591-4. Epub 2009 May 31.
Epidermoid carcinoma of the penis presents in 1% of malignant tumors in men. Penis cancer treatment has traditionally been total or partial amputation. There are authors who consider radiation to be part of penis cancer treatment in select cases--especially the use of brachytherapy and external radiation.
The case of a 48-year-old male who in 2004 presented with an ulcerated lesion of the penis that was left unattended to is presented. Two years later, he sought medical attention and physical examination revealed an ulcerated penile lesion with poorly defined edges and limited to the glans.
The lesion was biopsied and the histopathological study reported Epidermoid Carcinoma. After radiological studies, it was classified as stage T2-N0-M0.
Total penectomy without lymphadenectomy was performed. The patient received adjuvant treatment of 15 sessions of cobalt radiation treatment at a dose of 3,500 cGy. Six months later, the patient noticed the presence of erythema at the genital and inguinal level which later ulcerated and extended toward the perineum. The disease progressed tragically and the patient died 2 years later.
阴茎表皮样癌占男性恶性肿瘤的 1%。阴茎癌的传统治疗方法为全切除或部分切除。有作者认为,在某些情况下,包括近距离放射治疗和外照射在内的放射治疗可作为阴茎癌的治疗方法之一。
报告了一名 48 岁男性的病例,他于 2004 年出现阴茎溃疡性病变,未予治疗。两年后,他寻求医疗救治,体格检查显示阴茎有溃疡性病变,边缘不清,局限于龟头。
对病变进行了活检,组织病理学研究报告为表皮样癌。经过影像学研究,该患者被归类为 T2N0M0 期。
行全阴茎切除术,未行淋巴结清扫术。患者接受了 15 次钴 60 放疗,剂量为 3500cGy。6 个月后,患者发现生殖器和腹股沟部位出现红斑,随后溃疡并向会阴部位延伸。病情恶化,患者在 2 年后死亡。