Nowak Agnieszka, Kaciński Marek
Paediatric and Adolescent Neurology, Jagiellonian University Medical College, kraków.
Neurol Neurochir Pol. 2009 Mar-Apr;43(2):162-72.
Transcranial Doppler (TCD) enables indirect assessment of cerebral circulation by measurement of cerebral blood flow velocity. Stenosis and occlusion of cerebral vessels or cerebral vasospasm can be detected with this non-invasive method. Moreover, changes in cerebral blood flow velocity in response to hypercapnia or hypocapnia, exercise, temperature, orthostatic stress, visual and intellectual stimulation can be recorded and vasoreactivity or autoregulation mechanisms assessed. Migraine is considered to be a vasomotor disorder; its pathogenesis, however, is complex and requires further studies. TCD may help to detect mechanisms leading to migraine attack as well as during the attack and help to understand its pathophysiology. In this paper, the results of TCD examination in migraine patients in headache-free periods and during the attacks, in basal condition and during different stimulations, are presented. The influence of triptans on cerebral circulation is also described. Additionally, the role of TCD in diagnosis of patent foramen ovale in migraineurs is discussed.
经颅多普勒（TCD）通过测量脑血流速度对脑循环进行间接评估。采用这种非侵入性方法可检测脑血管的狭窄、闭塞或脑血管痉挛。此外，还可记录高碳酸血症或低碳酸血症、运动、温度、体位性应激、视觉和智力刺激引起的脑血流速度变化，并评估血管反应性或自动调节机制。偏头痛被认为是一种血管舒缩障碍；然而，其发病机制复杂，需要进一步研究。TCD可能有助于检测导致偏头痛发作的机制以及发作期间的机制，并有助于理解其病理生理学。本文介绍了偏头痛患者在无头痛期和发作期间、基础状态下以及不同刺激期间的TCD检查结果。还描述了曲坦类药物对脑循环的影响。此外，还讨论了TCD在偏头痛患者卵圆孔未闭诊断中的作用。
