Behnke J M, Eira C, Rogan M, Gilbert F S, Torres J, Miquel J, Lewis J W
School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Parasitology. 2009 Jun;136(7):793-804. doi: 10.1017/S0031182009006039.
We analysed 3 independently collected datasets of fully censused helminth burdens in wood mice, Apodemus sylvaticus, testing the a priori hypothesis of Behnke et al. (2005) that the presence of the intestinal nematode Heligmosomoides polygyrus predisposes wood mice to carrying other species of helminths. In Portugal, mice carrying H. polygyrus showed a higher prevalence of other helminths but the magnitude of the effect was seasonal. In Egham, mice with H. polygyrus showed a higher prevalence of other helminth species, not confounded by other factors. In Malham Tarn, mice carrying H. polygyrus were more likely to be infected with other species, but only among older mice. Allowing for other factors, heavy residual H. polygyrus infections carried more species of other helminths in both the Portugal and Egham data; species richness in Malham was too low to conduct a similar analysis, but as H. polygyrus worm burdens increased, so the prevalence of other helminths also increased. Our results support those of Behnke et al. (2005), providing firm evidence that at the level of species richness a highly predictable element of co-infections in wood mice has now been defined: infection with H. polygyrus has detectable consequences for the susceptibility of wood mice to other intestinal helminth species.
我们分析了3个独立收集的关于林姬鼠（Apodemus sylvaticus）体内蠕虫负荷的全面普查数据集，以检验Behnke等人（2005年）的先验假设，即肠道线虫多枝细颈线虫（Heligmosomoides polygyrus）的存在会使林姬鼠更容易携带其他种类的蠕虫。在葡萄牙，携带多枝细颈线虫的小鼠感染其他蠕虫的患病率更高，但这种影响的程度具有季节性。在伊格姆，携带多枝细颈线虫的小鼠感染其他蠕虫种类的患病率更高，且不受其他因素干扰。在马尔姆湖，携带多枝细颈线虫的小鼠更有可能感染其他种类的蠕虫，但仅在老年小鼠中如此。考虑到其他因素，在葡萄牙和伊格姆的数据中，多枝细颈线虫的重度残留感染都携带了更多种类的其他蠕虫；马尔姆的物种丰富度太低，无法进行类似分析，但随着多枝细颈线虫虫负荷的增加，其他蠕虫的患病率也随之增加。我们的结果支持了Behnke等人（2005年）的研究结果，有力地证明了在物种丰富度层面，现已确定了林姬鼠共感染中一个高度可预测的因素：感染多枝细颈线虫对林姬鼠感染其他肠道蠕虫种类的易感性有可检测到的影响。
