Department of Surgery and Transplantation, Liver and Multi-organ Transplantation, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Pathol Res Pract. 2010 Apr 15;206(4):282-6. doi: 10.1016/j.prp.2009.04.012. Epub 2009 May 31.
Malignant mixed tumors of the liver in adults are extremely rare. To our knowledge, only a few cases have been reported in the literature. Nested stromal-epithelial tumors (NSET) of the liver are characterized by non-hepatocytic, non-biliary tumors with nests of epithelial and spindle cells, an associated myofibroblastic stroma, as well as variable calcifications and ossifications. We report a case of NSET of the liver affecting a young woman and provide detailed histological and clinical follow-up data, adding an additional case of this extremely rare pathology to the literature.
成人肝脏的恶性混合瘤极为罕见。据我们所知,文献中仅报道过少数几例。肝脏巢状间质-上皮肿瘤(NSET)的特征是非肝细胞性、非胆管性肿瘤,具有巢状上皮和梭形细胞、相关的肌纤维母细胞基质,以及可变的钙化和骨化。我们报告了一例年轻女性肝脏 NSET 的病例,并提供了详细的组织学和临床随访数据,为该极其罕见的病理学增加了另一个病例。