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英国体育界对检测生长激素滥用问题的看法。

The UK Sport perspective on detecting growth hormone abuse.

作者信息

Stow M R, Wojek N, Marshall J

机构信息

UK Sport, 2nd Floor, 40 Bernard Street, London, WC1N 1ST, United Kingdom.

出版信息

Growth Horm IGF Res. 2009 Aug;19(4):375-7. doi: 10.1016/j.ghir.2009.04.014. Epub 2009 May 31.

Abstract

BACKGROUND AND OBJECTIVES

Human growth hormone (hGH) is seen as a doping risk in sport because of its possible anabolic and lipolytic effects. As a result of this hGH is prohibited for athletes to use both in and out-of-competition by the World Anti-Doping Agency (WADA) requiring Anti-Doping Organisations to work with research teams in identifying ways to detect hGH abuse.

APPROACH

This paper reviews and discusses the UK Sport perspective on the challenges faced in detecting hGH and in particular draws upon the experiences gained during the collaborative efforts with the GH-2004 research team in achieving the implementation of the Marker Method for hGH detection.

CONCLUSIONS

In 2008 significant progress has been made; there is one test for detecting HGH approved for use in anti-doping and a second detection method pending. This is a strong reflection of the ongoing research efforts in anti-doping and the progress being made by the Anti-Doping Organisations in reducing the risk that doping poses to sport.

摘要

背景与目标

由于人生长激素(hGH)可能具有合成代谢和脂肪分解作用,在体育界被视为一种兴奋剂风险。因此,世界反兴奋剂机构(WADA)禁止运动员在比赛期间和非比赛期间使用hGH,要求反兴奋剂组织与研究团队合作,寻找检测hGH滥用的方法。

方法

本文回顾并讨论了英国体育界对检测hGH所面临挑战的观点,特别是借鉴了与GH - 2004研究团队合作实施hGH检测标记法过程中获得的经验。

结论

2008年取得了重大进展;有一种检测hGH的方法已被批准用于反兴奋剂检测,另一种检测方法正在审批中。这充分反映了反兴奋剂领域正在进行的研究工作,以及反兴奋剂组织在降低兴奋剂对体育造成的风险方面所取得的进展。

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