Cardiovascular Engineering and Medical Devices Group, Department of Mechanical Engineering, University College London, Torrington Place, London WC1 7JE, UK.
Philos Trans A Math Phys Eng Sci. 2009 Jul 13;367(1898):2655-66. doi: 10.1098/rsta.2009.0052.
This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective.
本文描述了多种软件工具在心血管应用中的使用。这些工具主要是在工程领域开发的,所提出的应用程序推动了软件的边界扩展,以解决与静脉和动脉瓣关闭、探索动态边界条件或包括从蛋白质到器官水平的多尺度边界条件相关的事件。从最终用户的角度讨论了心血管研究的未来以及建模者和临床医生在从验证到临床应用中面临的挑战。