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"Dwarf" estrogen receptor in breast cancer and resistance to tamoxifen.

作者信息

Fowler Amy M, Santen Richard J, Allred D Craig

出版信息

J Clin Oncol. 2009 Jul 20;27(21):3413-5. doi: 10.1200/JCO.2009.21.8776. Epub 2009 Jun 1.

DOI:10.1200/JCO.2009.21.8776
PMID:19487375
Abstract
摘要

相似文献

1
"Dwarf" estrogen receptor in breast cancer and resistance to tamoxifen.
J Clin Oncol. 2009 Jul 20;27(21):3413-5. doi: 10.1200/JCO.2009.21.8776. Epub 2009 Jun 1.
2
ZIP restores estrogen receptor expression and response to Tamoxifen in estrogen receptor negative tumors.
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A new marker of tamoxifen resistance of estrogen receptor-positive breast cancer.雌激素受体阳性乳腺癌对他莫昔芬耐药的一种新标志物。
Dokl Biochem Biophys. 2007 Mar-Apr;413:83-7. doi: 10.1134/s1607672907020123.
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Menin, a product of the MENI gene, binds to estrogen receptor to enhance its activity in breast cancer cells: possibility of a novel predictive factor for tamoxifen resistance.Menin 是 MENI 基因的产物,与雌激素受体结合以增强其在乳腺癌细胞中的活性:一种新的他莫昔芬耐药预测因子的可能性。
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[Expression of hormonal receptors (alpha-estrogen, beta-estrogen, progesteron), Ki-67 and P53 in endometrium of tamoxifen treated breast cancer patients].[他莫昔芬治疗的乳腺癌患者子宫内膜中激素受体(α-雌激素、β-雌激素、孕激素)、Ki-67和P53的表达]
Rev Med Chir Soc Med Nat Iasi. 2011 Jul-Sep;115(3):834-8.
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A Novel Functional Domain of Tab2 Involved in the Interaction with Estrogen Receptor Alpha in Breast Cancer Cells.一种参与乳腺癌细胞中与雌激素受体α相互作用的Tab2新功能结构域。
PLoS One. 2016 Dec 19;11(12):e0168639. doi: 10.1371/journal.pone.0168639. eCollection 2016.
7
MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance.丝裂原活化蛋白激酶/雌激素受体相互作用增强雌激素介导的信号传导和肿瘤生长,但不赋予他莫昔芬耐药性。
Oncogene. 2002 Jun 6;21(25):4000-8. doi: 10.1038/sj.onc.1205506.
8
Tamoxifen resistance and metastasis of human breast cancer cells were mediated by the membrane-associated estrogen receptor ER-α36 signaling in vitro.体外研究表明,膜相关雌激素受体 ER-α36 信号转导介导了他莫昔芬耐药和人乳腺癌细胞的转移。
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A metastatic breast tumor cell line, GI-101A, is estrogen receptor positive and responsive to estrogen but resistant to tamoxifen.一种转移性乳腺癌细胞系GI-101A,雌激素受体呈阳性,对雌激素有反应,但对他莫昔芬耐药。
Cell Biol Int. 1998;22(6):413-9. doi: 10.1006/cbir.1998.0269.
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Selenium disrupts estrogen receptor (alpha) signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells.硒可破坏雌激素受体(α)信号传导,并增强对子宫内膜癌细胞和耐他莫昔芬乳腺癌细胞中他莫昔芬的拮抗作用。
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引用本文的文献

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Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer.β蛋白1同源异型蛋白通过与乳腺癌中的雌激素受体结合来诱导细胞生长和雌激素非依赖性肿瘤发生。
Oncotarget. 2016 Aug 16;7(33):53204-53216. doi: 10.18632/oncotarget.10633.
2
Chaperone gp96 mediates ER-α36 cell membrane expression.伴侣蛋白gp96介导雌激素受体α36的细胞膜表达。
Oncotarget. 2015 Oct 13;6(31):31857-67. doi: 10.18632/oncotarget.5273.
3
miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets.
受雌激素、他莫昔芬和内分泌干扰物调控的微小RNA及其下游基因靶点。
Mol Cell Endocrinol. 2015 Dec 15;418 Pt 3(0 3):273-97. doi: 10.1016/j.mce.2015.01.035. Epub 2015 Feb 3.
4
Daidzein-estrogen interaction in the rat uterus and its effect on human breast cancer cell growth.大豆黄素与大鼠子宫内雌激素的相互作用及其对人乳腺癌细胞生长的影响。
J Med Food. 2012 Dec;15(12):1081-90. doi: 10.1089/jmf.2011.0322. Epub 2012 Dec 10.
5
ER-α36, a novel isoform of ER-α66, is commonly over-expressed in apocrine and adenoid cystic carcinomas of the breast.ER-α36,一种 ER-α66 的新型异构体,在乳腺的大汗腺癌和腺样囊性癌中常过度表达。
J Clin Pathol. 2011 Jan;64(1):54-7. doi: 10.1136/jcp.2010.082776. Epub 2010 Nov 2.
6
Estrogen receptor alpha 46 is reduced in tamoxifen resistant breast cancer cells and re-expression inhibits cell proliferation and estrogen receptor alpha 66-regulated target gene transcription.雌激素受体α46 在他莫昔芬耐药乳腺癌细胞中减少,重新表达可抑制细胞增殖和雌激素受体α66 调节的靶基因转录。
Mol Cell Endocrinol. 2010 Jul 29;323(2):268-76. doi: 10.1016/j.mce.2010.03.013. Epub 2010 Mar 17.